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ProteomicsQuantitative differences in rumen epithelium proteins in lambs fed wheat, perennial wheat or perennial wheat plus lucerne.
The rumen is a major the site of digestion and absorption of energy predominantly in the form of short chain fatty acids as well as amino acids and simple carbohydrates. The value of crops such as perennial wheat (PW) for grain and grazing compared to conventional wheat (W), or the addition of lucer...
ORGANISM(S): Ovis aries 
2023-10-24 | PXD044135 | Pride
Epithelium Nutrient Transport Tmt-ms Rumen Proteome Membrane 
ProteomicsPseudomonas aeruginosa proteome under hypoxic stress conditions mimicking the cystic fibrosis lung
Pseudomonas aeruginosa is a Gram-negative, opportunistic bacterium and a major etiological agent in monogenic disease cystic fibrosis (CF). High density colonies of P. aeruginosa are often isolated from hypoxic mucus plugs in respiratory tract of CF patients, indicating high adaptive capacities of t...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2017-08-29 | PXD007233 | Pride
Cystic fibrosis Hypoxia Pseudomonas aeruginosa Tmt-ms Swath-ms 
ProteomicsQuantitative differences in rumen epithelium proteins, as well as body composition and metabolizable energy intake in lambs fed a low or high energy diet.
The rumen is a major the site of digestion and absorption of energy predominantly in the form of short chain fatty acids as well as amino acids and simple carbohydrates. The research sought to determine if diets high or low in ME were associated with quantitative changes in the membrane bound protei...
ORGANISM(S): Ovis aries 
2026-02-09 | PXD054700 | Pride
Epithelium Nutrient Transport Rumen Membrane 
ProteomicsQuantitative Proteome of enzymatically isolated rumen epithelium in sheep with low or high methane emission.
Ruminant livestock are one of the major contributors to carbon emission contributing the global warming issue. Methane (CH4) produced from enteric microbial fermentation of feed in the reticulo-rumen are known to differ between sheep with different digestive function and fermentation products such a...
ORGANISM(S): Ovis aries 
2023-03-11 | PXD026538 | Pride
Sheep Swath-ms Membrane proteome Rumen epithelium 
ProteomicsTMT-based quantitative proteomic assessment of Vicia sativa induced neurotoxicity by β-cyano-L-alanine and γ-glutamyl-β-cyano-L-alanine in SH-SY5Y cells
β-Cyano-L-alanine (BCA) and γ-glutamyl-β-cyano-L-alanine (GBCA) are the primary antinutritional compounds in Vicia sativa, a high-protein, drought-tolerant legume. While neurotoxicity in monogastric animals has been observed, its molecular basis remains largely unknown. In this study, we optimised a...
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD067726 | Pride
Neurotoxicity Vicia sativa Tmt-based proteomics Sh-sy5y cells 
ProteomicsTwo of a kind: Transmissible Schwann cell cancers in the endangered Tasmanian devil.
Devil facial tumour disease 1 and 2 (DFT1 and DFT2) are two genetically distinct transmissible cancers endangering the survival of the Tasmanian devil (Sarcophilus harrisii). DFT1 first arose from a cell of the Schwann cell lineage, however, the tissue-of-origin of the recently discovered DFT2 cance...
ORGANISM(S): Sarcophilus harrisii 
2019-08-06 | PXD011209 | Pride
Tasmanian devil Swath Devil facial tumour disease Proteomics 
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