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ProteomicsIdentification of CDK1 phosphorylation of TFCP2L1 from murine embryonic stem cells and bladder cancer cells
Molecular programs involved in embryogenesis are frequently upregulated in oncogenic dedifferentiation and metastasis. However, their precise roles and regulatory mechanisms remain elusive. Here, we showed that CDK1 phosphorylation of TFCP2L1, a pluripotency-associated transcription factor, orches...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2019-11-08 | PXD015635 | Pride
Pluripotency Cdk1 Stemness features Embryonic stem-cell Bladder cancer 
ProteomicsIdentification of the acetylated lysine residues of Dnmt3L protein in murine embryonic stem cells
The core purpose of this project is to identify the novel epigenetic factors which play a crucial role on regulating stem cells developed from embryo development to ageing through the longitudinal analysis of their transcriptome, protein interactome, and post- translational modification network. Thu...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-26 | PXD032953 | Pride
Dna methyltransferases (dnmts) Embryonic stem cell (esc) Gel-lc-ms/ms Mus musculus (mouse) Proteome Acetylation 
ProteomicsMouse muscle proteome for sarcopenia study
Aging and lack of exercise are ones of most important attributing causes of muscle loss. To find a novel factor contributing to muscle loss, we performed mass spectrometry-based proteomic analysis in gastrocnemii of unloading and old mice compared to those of exercised and young mice.
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD043715 | Pride
Muscle Mouse Lc-ms Sarcopenia Lfq 
ProteomicsT2D patients’ urine LC-MSMS for predicting prognosis w/ and w/o renal dysfunction
Renal dysfunction and its functional regression have been known as one of major complication of type 2 diabetes (T2D). The prognosis for kidney function can be determined by estimated glomerular filtration rate (eGFR) and the known protein makers such as albumin and those parameters can classy patie...
ORGANISM(S): Homo sapiens (Human) 
2020-06-23 | PXD016571 | Pride
Human Lc-msms Diabetes mellitus type 2 Kidney Diabetic nephropathy Urine 
ProteomicsPlasma proteome signature to predict outcome of breast cancer patients receiving neoadjuvant chemotherapy
The purpose of this study is to find candidate biomarkers by analyzing proteins with differential amounts in 17 breast cancer patients’ plasmas with pathological complete response and 34 breast cancer patients’ plasmas without pathological complete response.
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD028251 | Pride
Human Lc-msms Pathological complete response Breast cancer Neoadjuvant chemotherapy Proteome Plasma 
ProteomicsConvergence of plasma metabolomics and proteomics analysis to discover signatures of high-grade serous ovarian cancer
The purpose of this study is to find candidate biomarkers by analyzing metabolites and proteins with differential amounts in 10 ovarian cancer patient plasmas and 10 healthy female plasmas. Only MS files for plasma proteins are uploaded here. The metabolite quants were obtained using Biocrates Absol...
ORGANISM(S): Homo sapiens (Human) 
2020-12-01 | PXD020557 | Pride
Human Lc-msms Metabolome Plasma Ovarian cancer Proteome 
ProteomicsComparative analysis of therapeutic effects between medium cut-off and high flux dialyzers using metabolomics and proteomics
This study compared the therapeutic effects of medium cut-off (MCO) and high flux (HF) dialyzers using metabolomics and proteomics. This was a single-center prospective trial of 20 patients receiving maintenance hemodialysis (HD). A consecutive dialyzer membrane was used for 15-week study periods as...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD026907 | Pride
Human Lc-msms Plasma Swath-ms Homodialysis 
ProteomicsProteomic analysis of breast cancer based on immune subtypes
Immunotherapy is applied to breast cancer to resolve the limitations of survival gain in existing treatment modalities. With immunotherapy, a tumor can be classified into immune-inflamed, excluded and desert based on the distribution of immune cells. We assessed the clinicopathological features, eac...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD043902 | Pride
Ffpe Proteome Lfq Breast cancer Immune subtype 
ProteomicsComparative proteome of membrane proteome from Lactobacillus fermentum MI37
Recent findings have positioned the gut microbiota as a promising target to enhance cancer immunotherapy. However, the specific microbial molecules that drive anti-tumor immunity remain unclear. Here, we identify a human-derived strain, Lactobacillus fermentum MI37, that potentiates anti-cancer immu...
ORGANISM(S): Escherichia coli 
2026-05-25 | PXD071250 | Pride
Anti-cancer Lactobacillus fermentum mi37 Lc-ms Ifn-gamma Membrane proteome 
ProteomicsProteomic profiling of canine (dog) serum and urine
Companion dog care market is annually increasing. A relationship with a dog who lives with humans gives a lot of psychological stability. Therefore, companion dog's health is important to the owner. It would be of great help if a non-invasive method could monitor health through bodily fluids (urine,...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2023-04-05 | PXD034770 | Pride
Canis lupus familiaris Serum Spectrum library Urine Lc-ms/ms 
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