Sort   by:  
 Page size 
ProteomicsThe metabolic background is a global player in Saccharomyces gene expression epistasis
The transcriptome, proteome and metabolome of 16 S.cerevisiae backgrounds, combinatorially perturbed in HIS3, LEU2, URA3 and MET15strains are compared. The project was jointly supervised by Kathryn Lilley and Markus Ralser. Transcriptome data has been deposited at ArrayExpress under accession
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-01-05 | PXD001491 | Pride
S. cerevisiae 
ProteomicsCyanobacterial proteome mapping reveals distinct compartment organisation and metabolism dispersed throughout the cell
Cyanobacteria are complex prokaryotes, incorporating a Gram-negative cell wall and internal thylakoid membranes (TM). However, localisation of proteins within cyanobacterial cells is poorly understood. Using subcellular fractionation and quantitative proteomics we report the first subcellular map of...
ORGANISM(S): Bacteria Synechocystis sp. PCC 6803 
2019-10-31 | PXD014662 | Pride
Cyanobacteria Lopit Synechocystis Spatial proteomics 
ProteomicsDrosophila nicotinic acetylcholine receptor subunits and their native interactions with insecticidal peptide toxins
Description Drosophila melanogaster nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that present a target for insecticides. However, a better understanding of in vioreceptor subunit composition is needed for effective design of insecticides. Alpha-neurotxins are known as pe...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-10-11 | PXD028484 | Pride
Nachrs Pull-down Toxins Smalps 
ProteomicsBiotin proximity tagging favors unfolded proteins and enables the study of intrinsically disordered regions
Intrinsically Disordered Regions (IDRs) are enriched in disease-linked proteins known to have multiple post-translational modifications, but there is limited in vivo information about how locally unfolded protein regions contribute to biological functions. We reasoned that IDRs should be more access...
ORGANISM(S): Escherichia coli 
2020-01-29 | PXD016422 | Pride
Lc-sps-ms3 E. coli H. sapiens Idr Biotin 
ProteomicsThe distinct roles of genome, methylation, transcription, and translation on protein expression in Arabidopsis thaliana resolve the Central Dogma’s information flow
A label-free proteomics dataset from our investigation of the interplay of constitutive gene-body CpG methylation (gbM), tRNA abundance and codon composition on mRNA and protein expression, in the plant Arabidopsis thaliana. We performed genomic profiling in rosette leaves of two Arabidopsis accessi...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-07-31 | PXD058342 | Pride
Dia Arabidopsis Leaf Diapasef Can-0 Col-0 
ProteomicsSpectral library of Solanum lycopersicum for SWATH-MS
A spectral library was built for Solanum lycopersicum. The spectral library allows reproducible quantification for thousands of peptides per SWATH-MS analysis. Proteins from Solanum lycopersicum pericarp were digested with trypsin using in-gel digestion and the peptides were fractionated by high-pH...
ORGANISM(S): Solanum Lycopersicum (ncbitaxon:4081) 
2017-05-11 | MSV000081074 | MassIVE
ProteomicsSpectral library of Drosophila melanogaster for SWATH-MS
A spectral library was built for Drosophila melanogaster. The spectral library allows reproducible quantification for thousands of peptides per SWATH-MS analysis. Proteins from Drosophila melanogaster embryo, adult flies were digested with trypsin using in-gel digestion and the peptides were fracti...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2017-05-11 | MSV000081075 | MassIVE
ProteomicsExtrarenal ?-klotho expression in human tissues
?-Klotho has emerged as a powerful regulator of the ageing process. To-date, the expression profile of ?-Klotho in human tissues is unknown and its existence in some human tissue types is subject to much controversy. Objective: This is the first study to characterize system-wide tissue expression of...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080719 | MassIVE
ProteomicsAdditional precursor purification in isobaric mass tagging experiments by traveling wave ion mobility separation (TWIMS).
We investigated if additional peptide purification by traveling wave ion mobility separation (TWIMS) can reduce precursor contamination using a mixture of S. cerevisiae and HeLa proteomes. In accordance with previous reports on FAIMS-Orbitrap instruments, we find that TWIMS provides a remarkable imp...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2014-06-10 | PXD001047 | Pride
Ims Tmt Ion mobility separation Isobaric mass tag Tandem mass tag Travelling wave ion mobility separation Twims 
ProteomicsProteomics of Intracellular Freezing Survival
Panagrolaimus sp. DAW1, a nematode cultured from the Antarctic, has the extraordinary physiological ability to survive total intracellular freezing throughout all of its compartments. While a few other organisms, all nematodes, have subsequently also been found to survive freezing in this manner, P....
ORGANISM(S): Panagrolaimus 
2020-05-01 | PXD018121 | Pride
Intracellular freezing Nematode Panagrolaimus Cryoprotection 
Sort   by:  
 Page size