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ProteomicsDeep proteomic and phosphoproteomic profiling of neuroblastoma treated with XPO1 inhibitor Selinexor
Neuroblastoma accounts for 15% of cancer-related deaths in children, highlighting an unmet need for novel therapies. Selinexor is a small molecule inhibitor of XPO1 that shuffles cargo proteins with a nuclear export sequence, many of which are essential for cancer growth and cell maintenance, from t...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026454 | Pride
Tmtpro Phosphoproteome Selinexor Xpo1 Neuroblastoma Proteome 
UnknownDevelopment of new cytogenetic markers for Thinopyrum ponticum (Podp.) Z.-W. Liu & R.-C. Wang.
Not available
S-EPMC6702164 | biostudies-literature
ProteomicsDeep proteomic and phosphoproteomic profiling of DIPG responses to radiation therapy
Different DIPG tumor models have different responses to radiation therapy, which can be identified by quantitative proteomics/phospho-proteomics approach
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD028285 | Pride
Cancer Radiation therapy Phosphoproteome Dipg Proteome 
UnknownIdentification of Alkaloids from Corydalisyanhusuo W. T. Wang as Dopamine D₁ Receptor Antagonists by Using CRE-Luciferase Reporter Gene Assay.
Not available
S-EPMC6222624 | biostudies-literature
UnknownNetwork pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of action of Wang Bu Liu Xing (Semen vaccariae) for colorectal cancer.
Not available
S-EPMC10186540 | biostudies-literature
UnknownCytotoxicity-guided isolation of elatostemanosides I-VI from <i>Elatostema tenuicaudatum</i> W. T. Wang and their cytotoxic activities.
Not available
S-EPMC11970508 | biostudies-literature
Proteomics6-Shogaol Inhibits Oxidative Stress-induced Rat Vascular Smooth Muscle Cell Apoptosis by Regulating OXR1-p53 axis
Apoptosis of vascular smooth muscle cells (VSMCs) is closely related to the pathogenesis of cardiovascular disease, and oxidative stress is an important cause for VSMCs death. Inhibiting VSMCs apoptosis is an effective preventive strategy in slowing down the development of cardiovascular disease, es...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-22 | PXD015127 | Pride
Lc-msms Rat Vascular smooth muscle cell 6-shogaol 
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
ProteomicsDeep proteomic and phosphoproteomic profiling of Rhabdoid tumor response to IDA/SEL therapy
Different Rhabdoid tumors have different responses to idasanultin/selinexor therapy, which can be identified by quantitative proteomics/phospho-proteomics approach
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD049344 | Pride
Human Pediatric Selinexor Idasanutlin Rhabdoid 
UnknownTwo new species and one new record of Parakiefferiella Thienemann, 1936 from China (Diptera, Chironomidae).
Not available
S-EPMC4714373 | biostudies-literature
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