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UnknownDesigning Cyclic Nitrogen-Bridged Sulfonamides with Anti-Cancer Activity.
Not available
S-EPMC12321273 | biostudies-literature
UnknownSynthesis and in vitro Study of Artemisinin/Synthetic Peroxide-Based Hybrid Compounds against SARS-CoV-2 and Cancer.
Not available
S-EPMC9086992 | biostudies-literature
UnknownUncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization.
Not available
S-EPMC11524979 | biostudies-literature
UnknownNon-orthosteric inhibition of enolase 1 impedes growth of triple-negative breast cancer.
Not available
S-EPMC12711674 | biostudies-literature
UnknownOne-Pot Gateway to Quinazoline-Thiohydantoin Fused Scaffolds and Discovery of Their Antileukemic Activity.
Not available
S-EPMC12933347 | biostudies-literature
UnknownInhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy.
Not available
S-EPMC11148772 | biostudies-literature
ProteomicsYB-1 inhibition suppresses osteosarcoma growth and reverses tumor immunosuppression
U2OS, and SaOS cells were treated with DMSO (vehicle control) or SU056 (24h). Quantitative proteomics analysis was performed on cell lysates.
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD074439 | Pride
Yb-1 Osteosarcoma Cell lines Treatment 
ProteomicsNon-allosteric Inhibition of Enolase 1 Impedes Growth of Triple-Negative Breast Cancer
1. Cellular Thermal Shift Assay (CETSA): MDA-MB-231 cells were treated for 6h with DMSO or SU212 and incubated at different temperatures and protein differences in the soluble fractions were determined. 2. Quantitative Proteomics: MDA-MB-231, MDA-MB-468, and BT549 cells were treated with DMSO (vehi...
ORGANISM(S): Homo sapiens (Human) 
2025-10-10 | PXD061466 | Pride
Non-allosteric inhibition Eno1 Aza-podophyllotoxin derivative Enolase Triple-negative breast cancer 
ProteomicsProteomics of Triple Negative Breast Cancer Cells Treated with SU056
1. Quantitative Proteomics: MDA-MB-231, MDA-MB-468, and MCF12A cells were treated with DMSO (vehicle control) or SU056 (novel small molecule drug candidate). Quantitative proteomics analysis was performed on cell lysates. 2. Cellular Thermal Shift Assay (CETSA): MDA-MB-231 cells were treated with D...
ORGANISM(S): Homo sapiens (Human) 
2024-04-04 | PXD042380 | Pride
Breast cancer Cell lines Triple negative Treatment 
UnknownNovel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer.
Not available
S-EPMC7851402 | biostudies-literature
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