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ProteomicsSerum proteomics reveals a sexually dimorphic effect of vitamin D status correction on proteins of the blood coagulation pathway among overweight adults
Background: An important feature to vitamin D physiology is its gender dependence. The aim of this study was to examine whether vitamin D exerts a sexually dimorphic effect on the blood coagulation pathway among adults with overweight. Methods: This study compared the serum proteomic profiles of age...
ORGANISM(S): Homo sapiens (Human) 
2016-10-13 | PXD003663 | Pride
Sexual dimorphism Vitamin d Blood coagulation Serum proteomics 
ProteomicsIntegrated proteomics and transcriptomics analysis identifies novel cell surface markers of HIV latency
Background: The cellular reservoir of latent HIV infection remains the main barrier to cure this virus. Elimination of this reservoir would be possible, if molecular identity of latently infected cells were fully elucidated. Biomarkers proposed previously were able to capture only a relatively small...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD024014 | Pride
Primary cd4+ t cells Transcriptome Plxnb2 Liquid chromatography mass spectrometry Ceacam1 Hiv latency Biomarkers Proteome Rna-seq 
ProteomicsEffects of in utero exposure to caloric restriction on the heart proteome of the foetus - Part2
Effects of in utero exposure to caloric restriction on the heart proteome of the foetus
ORGANISM(S): Rattus norvegicus (Rat) 
2021-08-01 | PXD011407 | Pride
Tmt Rattus norvegicus Lc-ms 
ProteomicsQuantitative proteomic profiling of fibroblasts in oesophageal adenocarcinoma
The accumulatiob of cancer-associated fibroblasts in tumours correlates with poor prognosis across cancer types including oesophageal adenocarcinoma. In this study we examined the proteomic profile of cancer-associated fibroblasts compared to normal fibroblasts.
ORGANISM(S): Homo sapiens (Human) 
2018-08-13 | PXD005444 | Pride
Lc-ms Proteomics Cancer associated fibroblasts 
ProteomicsIn utero exposure to caloric restriction and proteomic changes in foetal brain
In utero exposure to caloric restriction and proteomic changes in foetal brain
ORGANISM(S): Rattus norvegicus (Rat) 
2021-03-31 | PXD011394 | Pride
Lc-ms Tmt 
ProteomicsCorrection of cognitive deficits in mouse models of Down syndrome by pharmacological inhibitor of DYRK1A
Down Syndrome (DS) results from the trisomy of human chromosome 21 (HSA21). It is still the most frequent intellectual disability, affecting 1 newborn per 700 births. Among candidate genes explaining intellectual disabilities seen in DS patients, the dual specificity tyrosine-phosphorylation regulat...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-17 | PXD008419 | Pride
Kinase inhibitor Down syndrome Synapsin Dyrk1a Leucettine 
ProteomicsThe effect of bile acids on human placental proteome
The effects of bile acids on human placental proteome was examined
ORGANISM(S): Homo sapiens (Human) 
2019-11-14 | PXD009825 | Pride
Lc-ms Itraq Elite 
ProteomicsProteomic and phosphoproteomic profiling of human myoepithelial and luminal epithelial cells
The aim of the project is to perform deep proteomic and phosphoproteomic profiling of luminal epithelial and myoepithelial cells from the mammary gland of young vs. older women.
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD022691 | Pride
Proteomics Phosphoprotteomics Leps Meps 
ProteomicsDelta-like ligand 4-Notch signaling inhibition regulates pancreatic islet function and insulin secretion
Dll4-Notch signaling is required for cell fate decisions and neoplasias. However, emerging evidence suggests a role for Dll4-Notch signaling in metabolic and immune diseases. To date, there is no evidence of a direct effect of Dll4-Notch signaling inhibition on pancreatic islet function and insulin ...
ORGANISM(S): Mus musculus (Mouse) 
2018-08-13 | PXD005333 | Pride
Gsis Dll4 Diabetes 
ProteomicsEffects of in utero exposure to caloric restriction on the liver proteome of the foetus - Part1
Effects of in utero exposure to caloric restriction on the liver proteome of the foetus
ORGANISM(S): Rattus norvegicus (Rat) 
2021-03-23 | PXD011406 | Pride
Lc-ms Tmt 
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