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UnknownBeamline P02.1 at PETRA III for high-resolution and high-energy powder diffraction.
Not available
S-EPMC4416682 | biostudies-literature
Unknown3D-T1ρ prepared zero echo time-based PETRA sequence for in vivo biexponential relaxation mapping of semisolid short-T2 tissues at 3 T.
Not available
S-EPMC6816051 | biostudies-literature
ProteomicsN-terminal acetylome analyses reveals the substrate specificity profile of Naa50 (Nat5) and implicate NATs in influencing initiator Methionine processing
Co-translational N-terminal (Nt-) acetylation of nascent polypeptides is catalyzed by N-terminal acetyltransferases (NATs). The very N-terminal amino acid sequence is the major factor determining whether or not a given protein is Nt-acetylated. In humans, six different NATs, denoted NatA-NatF, are i...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-05-29 | PXD001437 | Pride
N-terminal acetyltransferase / n-terminomics / nt-acetylome / naa50 / nate 
UnknownInterleukin 33 and interleukin 4 regulate interleukin 31 gene expression and secretion from human laboratory of allergic diseases 2 mast cells stimulated by substance P and/or immunoglobulin E.
Not available
S-EPMC5827155 | biostudies-literature
UnknownAn overview of the use of psychoactive substances among students at the University of Lille during the COVID-19 health crisis: Results of the PETRA study.
Not available
S-EPMC10578082 | biostudies-literature
ProteomicsPARP1 proximity proteomics reveals interaction partners at stressed replication forks
PARP1 mediates poly-ADP-ribosylation of proteins on chromatin in response to different types of DNA lesions. PARP inhibitors are used for the treatment of BRCA1/2-deficient breast, ovarian, and prostate cancer. Loss of DNA replication fork protection is proposed as one mechanism that contributes to ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-11 | PXD037154 | Pride
Parp1 Proximity proteomics Ipond Olaparib Adp-ribosylation Tpx2 Replication stress 
ProteomicsUbiquitin-dependent transfer of PAF1c from MYC onto RNA Polymerase controls double-strand break repair at active promoters
MYC family proteins are oncogenic transcription factors that can globally affect the function of RNA Polymerase II (RNAPII). The ability of MYC proteins to promote transcription elongation depends on their ubiquitination, but the underlying mechanism and its biological relevance are unknown. Here we...
ORGANISM(S): Homo sapiens (Human) 
2021-02-15 | PXD023242 | Pride
Dna repair Rnapii Myc Paf1c Huwe1 
ProteomicsHakai is required for stabilization of core components of the m6A mRNA methylation machinery
N6-methyladenosine (m6A) is the most abundant internal modification on mRNA which influences most steps of mRNA metabolism and is involved in several biological functions. The E3 ubiquitin ligase Hakai was previously found in complex with components of the m6A methylation machinery in plants and mam...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-04-29 | PXD022294 | Pride
Rna modification M6a Sex determination Hakai 
ProteomicsProteogenomic Integration Reveals Therapeutic Targets in Breast Cancer Xenografts
Huang K, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, et al., (2017) Nature Communications | 8:14864 | DOI: 10.1038/ncomms14864 | http://www.nature.com/articles/ncomms14864

Recent advances in mass spectrometry (MS) hav...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084249 | MassIVE
ProteomicsComparative proteomics of Adult Paragominus kellikotti excretion/secretion products released in vitro or present in the lung cyst nodule
The aims of this study were to study ESPs to improve understanding of parasite-host interactions and to support the discovery of novel diagnostic or therapeutic targets. We used tandem mass-spectrometry to characterize the secretome of adult P. kellicotti flukes and to compare ESPs released during i...
ORGANISM(S): Paragominus Kellikotti 
2022-06-02 | MSV000089589 | MassIVE
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