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UnknownHigh-Throughput Microbore LC-MS Lipidomics to Investigate APOE Phenotypes.
Not available
S-EPMC10782415 | biostudies-literature
UnknownMicroflow LC-MS Bottom-Up Proteomics Using 1.5 mm Internal Diameter Columns.
Not available
S-EPMC11800007 | biostudies-literature
ProteomicsHigh-flow LC-MS/MS analyses - Conventional-Flow Liquid Chromatography-Mass Spectrometry for Exploratory Bottom-Up Proteomic Analyses
The major objective of our study was to find out what are the extra costs and what optimization and adjustment steps of a high-flow LC-MS system have to be undertaken to identify a comparable number of proteins as on a nanoLC-MS system.
ORGANISM(S): Homo sapiens (Human) 
2019-11-07 | PXD005481 | Pride
Microbore column Hela High-flow Narrow-bore column 
UnknownMeasurement of twenty-one serum steroid profiles by UPLC-MS/MS for the diagnosis and monitoring of congenital adrenal hyperplasia.
Not available
S-EPMC12550794 | biostudies-literature
MetabolomicsUntargeted metabolomics links glutathione to bacterial cell cycle progression
Cell cycle progression requires the coordination of cell growth, chromosome replication, and division. Consequently, a functional cell cycle must be coupled with metabolism. However, direct measurements of metabolome dynamics remained scarce, in particular in bacteria. Here, we describe an untargete...
2020-10-15 | MTBLS1402 | MetaboLights
ProteomicsProteome profiling of cell-free coelomic fluid from the common starfish Asterias rubens
Echinoderms, possessing outstanding regenerative capability, provide unique model system for the study of the response to injury. However, there is little known about the proteomic composition of coelomic fluid, an important biofluid circulating through the whole body and reflecting an overall biolo...
ORGANISM(S): Asterias rubens 
2019-03-15 | PXD010228 | Pride
Injury response Peptidase inhibitor Regeneration Orphan Wound healing Lc-maldi Biofluid Echinoderms Protein domain 
ProteomicsExploring direct and indirect targets of current antileishmanial drugs using a novel thermal proteomics profiling approach
We have implemented a novel approach based on thermal proteome profiling (TPP) to further characterize the mode of action of antileishmanials antimony, miltefosine and amphotericin B, as well as to better understand the mechanisms of drug resistance deployed by Leishmania.
ORGANISM(S): Leishmania infantum JPCM5 
2022-07-22 | PXD034836 | Pride
Leishmania  leishmaniasis  thermal proteome profiling  drug resistance  proteomics  antimony  miltefosine  amphotericin b 
ProteomicsProteome profiling of three cell populations from the common starfish Asterias rubens
The origin of cells involved in regeneration in Echinoderms is an open question till now. Most experimental data support the process of transdifferentiation as the main mechanism, although the activity of progenitor/stem cells is also considered. The renewal of coelomocytes, the cells which occupy t...
ORGANISM(S): Asterias rubens 
2020-12-09 | PXD012550 | Pride
Coelomic epithelium Progenitor cells Asterias rubens Lc-maldi Coelomocytes Sciex 5800 
ProteomicsTriple Null, a soybean bred to lack major seed allergen P34 and bioactive lectin and kunitz trypsin inhibitor
Seeds, including soybean (Glycine max), contain bioactive proteins with anti-nutritional and immunological properties that affect metabolism and assimilation of seed derived nutrients and as allergens that can induce escalating adverse immune responses. The presence of anti-nutritional proteins requ...
ORGANISM(S): Glycine max 
2022-02-23 | PXD000967 | Pride
Null Seed Soybean Allergen 
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