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The proteome changes were quantified in 1700030J22Rik-/- mouse sperm using Label-free by LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2024-12-25 | PXD052721 | Pride
Understanding molecular mechanisms of cellular pathways regularly requires knowledge of the identities of participating proteins, their cellular localization and their 3D structures. Contemporary workflows typically require multiple techniques to identify target proteins, track their localization us...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-21 | PXD036885 | Pride
Glycogen synthase kinase 3 alpha (GSK3α) has emerged as a prospective target to develop male contraceptives. The GSK3α paralog is highly conserved and present in the sperm of placental mammals. Global or testis-specific loss of GSK3α, but not GSK3β, results in male infertility. A preliminary study ...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-29 | PXD079474 | Pride
Sperm competition theory predicts that males should tailor ejaculates according to their social status. Here we test this in a model vertebrate, the house mouse (Mus musculus domesticus), combining experimental data with a quantitative proteomics analysis of seminal fluid composition. Our analyses r...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD019727 | Pride
The data contains 135 raw data produced from mass spectrometry (QExactive HF, Thermo Scientific), the bio-samples were sperm cells collected at nine sub-stages of mouse spermatogenesis. Proteins from each bio-samples were extracted and digested to peptides, then separated to five fractions and tripl...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-01 | PXD017284 | Pride
TEKT1/TEKT5/DUSP21/TSSK6 depletions cause changes in the proteomic level between KO and WT mouse
ORGANISM(S): Mus musculus (Mouse) 
2026-01-15 | PXD073076 | Pride
In the testis, Serine/arginine protein kinase 1 (SRPK1) and isoform 2 of Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP1γ) are essential proteins involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin s...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-31 | PXD054960 | Pride
In the testis, Serine/arginine protein kinase 1 (SRPK1) and isoform 2 of Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP1γ) are essential proteins involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin s...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-31 | PXD054959 | Pride
For decades, it was widely accepted that mammalian spermatozoa were devoid of translational activity due to the functional and morphological changes that occurred during spermatogenesis. However, it was proved that capacitated spermatozoa possess translation activity, which appears to be ensured by ...
ORGANISM(S): Bos taurus (Bovine) 
2025-06-13 | PXD050868 | Pride
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