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ProteomicsSugarQuant: a streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics
Site-specific regulation of protein N-glycosylation is essential in human cells. However, accurate quantification of glycosylation sites and their individual glycan moieties in a cell-wide manner is still technically challenging. Here, we introduce SugarQuant, an integrated mass spectrometry-based p...
ORGANISM(S): Homo sapiens (Human) 
2020-08-24 | PXD018349 | Pride
Glycosylation 
ProteomicsN-glyco db/db mouse kidney - N-glycosylation proteome enrichment analysis in kidney reveals differences between diabetic mouse models
N-glycosylated proteome of db/db diabetic mice with diabetic nephropathy, additional effect of insulin on db/db mice.
ORGANISM(S): Mus musculus (Mouse) 
2016-12-13 | PXD003349 | Pride
Db/db mice Mass spectrometry N-glycosylation N-glyco capture Insulin Diabetic nephropathy Diabetes 
ProteomicsN-glyco STZ mouse kidney - N-glycosylation proteome enrichment analysis in kidney reveals differences between diabetic mouse models
N-glycosylated proteome of STZ diabetic mice with diabetic nephropathy
ORGANISM(S): Mus Musculus 
2016-12-13 | PXD003196 | Pride
Proteomics Stz Kidney N-glycosylation Mass spectropmetry N-glyco proteome Diabetic nephropathy Diabetes 
UnknownAffinity-capture tandem mass spectrometric characterization of polyprenyl-linked oligosaccharides: tool to study protein N-glycosylation pathways.
Not available
S-EPMC2763189 | biostudies-literature
UnknownA streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics.
Not available
S-EPMC7572468 | biostudies-literature
UnknownShort report galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling.
Not available
S-EPMC10214663 | biostudies-literature
UnknownUnlocking Cancer Glycomes from Histopathological Formalin-fixed and Paraffin-embedded (FFPE) Tissue Microdissections.
Not available
S-EPMC5383776 | biostudies-literature
Proteomicsurinary glycopeptide profile differentiates early cardiorenal risk in subjects not meeting criteria for chronic kidney disease
Early diagnosis and treatment of chronic kidney disease (CKD) is a worldwide challenge. Albuminuria is defined as urinary albumin:creatinine ratio (ACR) ≥30 mg/g. Subjects with ACR values below this cut-off and preserved renal function are considered at no cardiorenal risk, but increased risk is est...
ORGANISM(S): Homo sapiens (Human) 
2025-06-02 | PXD049688 | Pride
Urine  glycopeptide  chronic kidney disease  early cardiorenal risk albuminuria 
ProteomicsInherited defect in ST6GalNAc1 reveals roles of sialylation in intestinal homeostasis
Chronic inflammatory bowel disease (IBD) causes disability, suffering and risk of colon cancer in over 30 million people globally. Here, we investigate 3 kindreds of IBD with mutations in the N-acetylgalactosamide alpha-2,6-sialyltransferase 1/ST6GALNAC1 (ST6) glycosyltransferase gene that is unique...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-03-17 | PXD028239 | Pride
Mus musculus (mouse) Orbitrap fusion lumos Homo sapiens (human) 
ProteomicsFunctional genomics identifies extension of complex N-glycans as a mechanism to evade lysis by natural killer cells
Somatic mutations can lead to the transformation of healthy cells into malignant cells and allow their evasion from immune surveillance. To uncover genes that play a role in the detection and lysis of tumor cells by natural killer (NK) cells, a B lymphoblastoid cell line was subjected to a genome-wi...
ORGANISM(S): Homo sapiens (Human) 
2024-03-19 | PXD040769 | Pride
N-glycan Sppl3 Natual killer cells Rituximab 
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