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ProteomicsGuard Cell Mitochondria Prefer Alternative Substrates and Energy-Conserving Electron Transfer
Proteomics of plant mitochondria usually is based on a bulk mixture of organelles originating from different leaf cell types. Here, a novel isolation technique was applied, fusing an affinity tag under control of cell type specific promotors to a mitochondrial outer envelope protein. The construct a...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2025-03-21 | MSV000097408 | MassIVE
ProteomicsFine-Tuning of Label-Free Single-Cell Proteomics Workflows
This project aims to compare three distinct workflows using different sample collection/preparation plate supports (EVO96 oil-free, LF48 oil-based and LF48 oil-free, a streamlined automated sample resuspension and direct injection protocol). Then, digestion efficiency using a range of protein/enzyme...
ORGANISM(S): Homo sapiens (Human) 
2025-12-12 | PXD067019 | Pride
Label-freescp 
ProteomicsIonizable polymeric micelles (IPMs) for efficient siRNA delivery
Lipid nanoparticles (LNPs) are widely used for nucleic acid delivery but face challenges like limited targeting and accelerated blood clearance. We design three ionizable oligo-mers (IOs) that, with PLA-PEG, form Ionizable Polymeric Micelles (IPMs), a potential siRNA delivery system, which can achie...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-21 | PXD057444 | Pride
Hsp47 Protein corona Hmgb1 Hepatic fibrosis Fibroblast activation protein inhibitor (fapi) Nucleic acid delivery Ionizable polymeric micelles (ipms) Hepatic stellate cells 
ProteomicsLolB is conserved in Bacteroidetes and is crucial for gliding motility and Type IX secretion.Part2
In Gram-negative bacteria, lipoproteins are major components of the outer membrane (OM) where they play a variety of roles, from the involvement in β-barrel assembly to virulence. Bacteroidetes, a widespread phylum of Gram-negative bacteria, including free-living organisms, commensals and pathogens,...
ORGANISM(S): Flavobacterium johnsoniae 
2025-02-22 | PXD059642 | Pride
Lipoprotein Transport Protein Bacteroidetes Membrane 
ProteomicsLolB is conserved in Bacteroidetes and is crucial for gliding motility and Type IX secretion.
In Gram-negative bacteria, lipoproteins are major components of the outer membrane (OM) where they play a variety of roles, from the involvement in β-barrel assembly to virulence. Bacteroidetes, a widespread phylum of Gram-negative bacteria, including free-living organisms, commensals and pathogens,...
ORGANISM(S): Flavobacterium johnsoniae 
2025-02-22 | PXD056078 | Pride
Lipoprotein Bacteroidetes Transport Membrane protein 
ProteomicsImmunoprecipitation-mass spectrometry (IP-MS) of USP15-interacting proteins in 786-O cells
786-O cells were lysed in IP buffer and processed for immunoprecipitation with anti-USP15 or normal rabbit IgG for 6 h at 4 °C. The immune complexes were incubated with Pierce Protein A/G Magnetic Beads (Thermo Scientific) overnight at 4 °C and washed with IP buffer. After SDS-PAGE and Coomassie bri...
ORGANISM(S): Homo Sapiens 
2026-03-26 | PXD076226 |
ProteomicsDIA proteomic profiling of dorsal skin from Dendrobium officinale polysaccharide-treated C57BL/6 mice
This project contains DIA-PASEF proteomics data generated from dorsal skin tissues of male C57BL/6 mice in a control group, a DHT-induced androgenetic alopecia (AGA) model group, and a Dendrobium officinale polysaccharide (DOP, 7.5 mg/mL)-treated group. The study was designed to investigate proteomi...
ORGANISM(S): Mus Musculus 
PXD077413 |
ProteomicsMass spectrometry-based phosphoproteomics of PCMD-1
PCMD-1 is a centriolar protein that stabilizes the pericentriolar material (PCM) scaffold in C. elegans. Our data show that CDK-1 primes PCMD-1 for PLK-1–dependent phosphorylation. Mutations in PLK-1 docking sites reduce PCMD-1 phosphorylation, leading to disorganized PCM, unstable centrosomes, and ...
ORGANISM(S): Caenorhabditis elegans 
2025-10-24 | PXD067573 | Pride
C. elegans 
ProteomicsID3 Deficiency Alters Chromatin Accessibility at DSB Sites and Enhances Vulnerability to HDAC Inhibition
The inhibitor of DNA-binding 3 (ID3) plays a crucial role in DNA double-strand break (DSB) repair. We previously reported that ID3 loss reduced chromatin accessibility at DNA repair gene promoters, yet its exact role in DNA repair via chromatin regulation remained elusive. Using the AID-DIvA cell sy...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD069605 | Pride
Id3 Chromatin accessibility Hdac Dsb Inhibition 
ProteomicsNEDDylation maintains oocyte quality by stabilizing mitochondrial transcription
As women age, their oocytes decline in both quantity and quality, leading to eventual infertility. Part of this decline is associated with increased levels of reactive oxygen species and decreased mitochondrial function, which are associated with lower live birth rates. However, detailed mechanisms ...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-06 | PXD076100 | Pride
Fertility Nedd8 Oocyte Proteomics Reproduction 
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