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TranscriptomicsReciprocal communication between endometrial stromal cells and macrophages
Endometriosis is an inflammatory disease and bone marrow-derived cells are abundant in endometriotic lesions and in the peritoneal fluid of women with the disease. This study tested the hypothesis that reciprocal communication occurs between macrophages and cultured human endometrial stromal cells ...
ORGANISM(S): Homo sapiens 
2010-07-21 | E-GEOD-19834 | biostudies-arrayexpress
ProteomicsA new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis
Accounting for more deaths than any other bacterial species, Mycobacterium tuberculosis (Mtb) represents a critical threat to public health worldwide. A key factor contributing to Mtb's virulence is its unique cell envelope, which acts as a protective barrier. Among the components of this envelope, ...
ORGANISM(S): Mycobacterium marinum ATCC BAA-535 Bacteria 
2025-12-12 | PXD069594 | Pride
Marinum Mycobacterium Tuberculosis Lipoarabinomannan Arabinogalactan 
ProteomicsCerebrospinal fluid proteomic analysis of long-term antihypertensive treatment with amlodipine and atenolol in hypertensive rats.
Hypertension is a risk factor for brain damage. Here we tested whether protection of the brain depends on the type of antihypertensive medication. We compared normotensive rats to untreated hypertensive rats and hypertensive rats treated with either amlodipine or atenolol. After one year treatment w...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-11-10 | PXD061968 | Pride
Csf Hypertensia Rat proteome 
ProteomicsProtein Kinase D drives the secretion of invasion mediators in triple negative breast cancer cell lines
Protein kinase D (PKD) regulates protein secretion at the Golgi complex and has been found to have a pro-oncogenic role in triple-negative breast cancer (TNBC). PKD was previously reported to regulate the secretion of tumor-promoting factors in prostate and pancreatic cancer. Whether PKD plays a sim...
ORGANISM(S): Homo sapiens (Human) 
2024-01-17 | PXD041042 | Pride
Secretion Proteomics Cytokine Invasion Tnbc Protein kinase d Tumor microenvironment Extracellular matrix Metastasis 
ProteomicsMicroglia display altered spatial morphology and proteome after stroke
Microglia are abundantly distributed throughout the central nervous system (CNS) to play critical roles in neural development and homeostasis, and act as immune sentinels to constantly monitor their surrounding neural environment. Given their high reactivity to brain insults, we hypothesised that th...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-22 | PXD055588 | Pride
Stroke Neuroinflammation Proteome Mouse Morphology Microglia 
Proteomicsabdominal aortic aneurysm (AAA) plasma proteomics
An abdominal aortic aneurysm (AAA) is a pathological dilatation of the aortic wall and it is a life-threatening disease due to the risk of rupture. Currently, surgical intervention remains the only definitive treatment recommended for large or rapidly expanding aneurysms. No pharmacological therapy ...
ORGANISM(S): Homo sapiens (Human) 
2026-05-21 | PXD068130 | Pride
Abdominal aortic aneurysm (aaa) Human Plasma Patient 
Proteomicsabdominal aortic aneurysm (AAA) proteomics
An abdominal aortic aneurysm (AAA) is a pathological dilatation of the aortic wall and it is a life-threatening disease due to the risk of rupture. Currently, surgical intervention remains the only definitive treatment recommended for large or rapidly expanding aneurysms. No pharmacological therapy ...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD067859 | Pride
Dia-ms Human tissue Abdominal aortic aneurysm 
ProteomicsLC-MS/MS proteomic analysis of human tissues
This project is to identify the presence of bacterial flagellins in human liver samples. Human liver protein lysates were separated on SDS-PAGE gels and visualized with Coomassie stain. The positions at which flagellins were detected using anti-flagellin antibodies from Covalab Inc. (France) and Abc...
ORGANISM(S): Homo sapiens (Human) 
2023-11-21 | PXD041941 | Pride
Liver Flagellin Human 
ProteomicsRBBP9 interactors in Fanconi Anaemia
The Fanconi Anaemia (FA) pathway resolves replication fork-stalling inter-strand crosslinks (ICLs) and is mutated in Fanconi anaemia. FA is a rare recessive chromosomal instability syndrome, resulting in hypersensitivity to DNA-crosslinkers, and particularly disadvantageous for stem cell growth and ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-27 | PXD026545 | Pride
Fanconi anaemia Rbbp9 Sirna screen Ip-ms Hnscc Label-free Flag 
ProteomicsProteomic analysis upon miR195/497 replacement reveals potential chemo sensitizing candidates for colorectal cancer
Patients with advanced colorectal cancer (CRC) are commonly treated with systemic combination therapy but suffer eventually from drug resistance. MicroRNAs (miRNAs) are suggested to play a role in treatment resistance of CRC. We studied whether restoring downregulated miR-195-5p and 497-5p sensitize...
ORGANISM(S): Homo sapiens (Human) 
2019-09-27 | PXD015369 | Pride
Label-free Mirna Microrna Colorectal cancer 
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