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ProteomicsSimple and efficient micro-SPE tip-based sample preparation workflow to enable sensitive proteomic profiling of limited samples
In-depth LC-MS-based proteomic profiling of limited samples has been problematic due, in large part, to the inefficiency of sample preparation and attendant sample losses. To address this issue, we developed On-Micro Solid-phase Extraction Tip-based (OmSET) sample preparation for limited biological...
ORGANISM(S): Homo sapiens (Human) 
2021-02-23 | PXD022313 | Pride
Micro-spe tip Omset Limited sample On-micro solid-phase extraction tip Sample preparation Stagetip 
TranscriptomicsTranscription profiling of Escherichia coli over-expressing genes involved in signaling systems that detect and respond to alterations of the bacterial envelope
The Bae, Cpx, Psp, Rcs and ?E pathways constitute the Escherichia coli signaling systems that detect and respond to alterations of the bacterial envelope. Contributions of these systems to stress response have previously been examined individually; however, the possible interconnections between thes...
ORGANISM(S): Escherichia coli 
2009-05-31 | E-MEXP-2139 | biostudies-arrayexpress
ProteomicsComparative Transcriptomics and Proteomics on Pi Depleted Arabidopsis Roots
Plant adaptation to limited phosphate (Pi) availability comprises a wide range of strategies to conserve and remobilize internal Pi stores and to enhance Pi acquisition. Vigorous restructuring of root system architecture provides a developmental strategy for topsoil exploration and Pi scavenging. Ch...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2016-05-06 | PXD003449 | Pride
Arabidopsis Phosphate Root Proteomics 
ProteomicsU87 Glioblastoma Cell-Derived Extracellular Vesicles Reflect 2D vs. 3D Culture Adaptations and Temozolomide Response
Glioblastoma (GBM) is an aggressive brain tumor marked by extensive heterogeneity, resistance to therapy, and dismal prognosis. Extracellular vesicles (EVs) have emerged as key players in GBM biology, mediating intercellular communication and therapy adaptation. However, the exact functions, signifi...
ORGANISM(S): Homo sapiens (Human) 
2026-08-15 | PXD069801 | Pride
Cancer Mass spectrometry Glioblastoma Extracellular vesicles U87 
ProteomicsA Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation
The B cell receptor (BCR) signals together with a multi-component co-receptor complex to initiate B cell activation in response to antigen binding. This process underlies nearly every aspect of proper B cell function. Here, we take advantage of peroxidase-catalyzed proximity labeling combined with q...
ORGANISM(S): Homo sapiens (Human) 
2024-06-06 | PXD040262 | Pride
Systems immunology Proteomics Bcr signaling B cell co-receptor B cells Phosphoproteomics 
Proteomics“phyloquant” to study the evolutionary relationships of organisms based on large scale quantitative protein expression
“phyloquant” to study the evolutionary relationships of organisms based on large scale quantitative protein expression
ORGANISM(S): Trypanosoma cruzi Trypanosoma rangeli SC58 Trypanosoma erneyi Trypanosoma dionisii Trypanosoma cruzi marinkellei 
2021-09-09 | PXD017228 | Pride
Phyloquant 
ProteomicsPalaeoproteomic analysis of ancient eggshell proteins from Çatalhöyük archaeological site
Palaeoproteomics analysis of archaeological bird eggshells from archaeological Çatalhöyük site. This project aimed to taxonomically identify fragments of eggshells from the site, using a combination of morphological observations (by light microscopy) and protein analyses (MALDI-MS and LC-MS/MS).
ORGANISM(S): Aves 
2020-06-10 | PXD014558 | Pride
Paleoproteomics Eggshells Archaeology Lc-ms/ms 
ProteomicsProteome profiling of cell-free coelomic fluid from the common starfish Asterias rubens
Echinoderms, possessing outstanding regenerative capability, provide unique model system for the study of the response to injury. However, there is little known about the proteomic composition of coelomic fluid, an important biofluid circulating through the whole body and reflecting an overall biolo...
ORGANISM(S): Asterias rubens 
2019-03-15 | PXD010228 | Pride
Injury response Peptidase inhibitor Regeneration Orphan Wound healing Lc-maldi Biofluid Echinoderms Protein domain 
ProteomicsTime-based quantitative proteomic and phosphoproteomic analysis of A549-ACE2 cells during SARS-CoV-2 infection
The outbreak of COVID-19, a disease caused by severe acute respiratory syndrome coronavirus 2, led to an ongoing pandemic with devastating consequences for the global economy and human health. With the globalspread of SARS-CoV-2, multidisciplinary initiatives were launched to explore new diagnostic,...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD053240 | Pride
Proteomics Virus-host interaction Sars-cov-2 Covid-19 
ProteomicsRestoring retinal polyunsaturated fatty acid balance and retina function by targeting ceramide in Adiponectin receptor 1 (AdipoR1) deficient mice
Mutations in the adiponectin receptor 1 gene (AdipoR1) lead to retinitis pigmentosa and are associated with age-related macular degeneration (AMD). This study explores the effects of AdipoR1 gene deficiency in mice, revealing a striking decline in ω3 polyunsaturated fatty acids (PUFA), an increase i...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-23 | PXD050916 | Pride
Proteomics Lipidomics Retinal pigment epithelium (rpe) Retina Polyunsaturated fatty acids (pufas) 
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