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ProteomicsImmunopeptidome of Renal Cell Carcinoma (RCC) and Bladder Cancer (BC) Patient-Derived Tumor Organoids (PDTOs)
Patient-Derived Tumor Organoids (PDTOs) have emerged as physiologically relevant systems, retaining genomic and phenotypic features of patient tumors and enabling drug response prediction. Here, we established a patient-specific pipeline to evaluate precision immunotherapy in Renal Cell Carcinoma (R...
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD068567 | Pride
Ligandome Pdtos Mhc Hla-i Dda Immunopeptidomics Hla Immunopeptidome Ligandomics Patient-derived tumor organoids Renal cell carcinoma Rcc Timstof scp Mhc-i Bladder cancer 
UnknownAdvancements in Research and Treatment Applications of Patient-Derived Tumor Organoids in Colorectal Cancer.
Not available
S-EPMC11311786 | biostudies-literature
UnknownValidation of a Novel EUS-FNB-Derived Organoid Co-Culture System for Drug Screening in Patients with Pancreatic Cancer.
Not available
S-EPMC10377599 | biostudies-literature
UnknownPatient-derived organoids inform pharmacogenomic vulnerabilities in liver cancer.
Not available
S-EPMC12205652 | biostudies-literature
TranscriptomicsEpithelial interferon-stimulated gene programs modulate chemotherapy sensitivity in colorectal cancer via EPSTI1
Precision oncology research typically utilizes patient-derived tumor organoids (PDTO) to predict clinical outcomes, but such efforts are often not directed towards identification of molecular factors underlying differential responses to therapy. Here, we performed bulk RNA-sequencing on treatment-na...
ORGANISM(S): Homo sapiens 
2026-06-30 | GSE292601 | GEO
TranscriptomicsRNA-seq analysis on organoids derived from metastatic tumor patients
To evaluate the efficiency of apatinib on vascularized patient-derived tumor organoids (PDTOs)-on-a-chip derived from patients with metastatic tumors, we conducted RNA-seq analysis on organoids derived from patients whom had metastatic tumors. Specifically, we extracted RNA for sequencing from tumor...
ORGANISM(S): Homo sapiens 
2024-04-27 | GSE264645 | GEO
UnknownCulture of patient-derived multicellular clusters in suspended hydrogel capsules for pre-clinical personalized drug screening.
Not available
S-EPMC8961426 | biostudies-literature
UnknownPatient-Derived Tumor Organoids for Drug Repositioning in Cancer Care: A Promising Approach in the Era of Tailored Treatment.
Not available
S-EPMC7761978 | biostudies-literature
Genomics0875359f-3f49-4472-91a0-e267517ed977 - samples
The dataset includes fastq files from 2 LCNEC tumors and matched PDTOs. The sequencing was done with either a Nextseq 2000 or a NovaSeq 6000 instrument.
EGAD00001009993 | EGA
Genomics538c7dbc-2c2b-4d79-a1d8-1f60abb767a5 - samples
The dataset includes fastq files from 4 NEN tumors or metastases and matched PDTOs. The sequencing was done with either a Nextseq 2000 or a NovaSeq 6000 instrument.
EGAD00001009991 | EGA
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