Sort   by:  
 Page size 
ProteomicsChromatin-associated proteome S. cerevisiae
Chromatin-associated and RNA-dependent Chromatin-associated proteome from S. cerevisiae, obtained by a new method yChEFs(yeast Chromatin Enriched Fractions)
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-07-17 | PXD009264 | Pride
Processing Rna Chromatin S. cerevisiae 
ProteomicsProteomic studies of es incorporation in S. cattleya WT and ΔbesG strains.
With in vitro biochemical studies showing that βes can be mistranslated for Thr and selectively edited by BesG, we sought to evaluate the ability of BesG to prevent in vivo misincorporation of βes in the native producer S. cattleya. We therefore disrupted the besG gene in S. cattleya and supplied βe...
ORGANISM(S): Streptantibioticus cattleyicolor 
2026-06-08 | PXD073884 | Pride
S. cattleya Beta-ethynylserine 
ProteomicsTLR9-Driven S-Palmitoylation in Dendritic Cells Reveals Immune and Metabolic Protein Targets
Dendritic cells (DCs) rely on Toll-like receptor 9 (TLR9) to detect unmethylated CpG motifs in microbial DNA, triggering essential immune responses. While the downstream signaling pathways of TLR9 activation are well characterized, their impact on S-palmitoylation is unknown. S-palmitoylation, invol...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-25 | PXD066223 | Pride
Tlr9 Dendritic cells. S-palmitoylation 
Genomics
Genomes of four grape accessions resistant to Pierce s disease
PRJNA1380937 | ENA
ProteomicsS-Nitrosylation-mediated dysfunction of TCA cycle enzymes in synucleinopathy studied in postmortem human brains and hiPSC-derived neurons
A causal relationship between mitochondrial metabolic dysfunction and neurodegeneration has been strongly implicated in synucleinopathies, including Parkinson’s disease (PD) and Lewy body dementia (LBD), but the underlying molecular basis is not fully understood. Here, using human induced pluripoten...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD036797 | Pride
S-nitrosylation Alpha-synuclein Tca cycle Mitochondrial dysfunction 
ProteomicsMouse Liver S-Palmitoylation ZDHHC13 LC-MS/MS
Protein S-palmitoylation is a reversible post-translational modification which adding 16-carbon palmitate to specific cysteines and contributes to variable biological functions such as protein trafficking, scaffolding and signaling. ZDHHC13 is one of the members of DHHC-containing palmitoyl-acyltran...
ORGANISM(S): Mus musculus (Mouse) 
2017-09-29 | PXD003039 | Pride
Zdhhc13 Mouse S-palmitoylation Liver Lc-ms/ms 
ProteomicsMetabolic bypass partially rescues S-nitrosylation-induced TCA cycle inhibition and synapse loss in Alzheimer’s disease human neurons
In Alzheimer’s disease (AD), dysfunctional mitochondrial metabolism has been associated with synaptic loss, the major pathological correlate of cognitive decline. Mechanistic insight for this relationship, however, is still lacking. Here, comparing isogenic wild-type and AD mutant human induced plur...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD042436 | Pride
S-nitrosylation Alzheimer’s disease Mitochondrial metabolism Tca cycle inhibition 
ProteomicsComparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines
Vector-based SARS-CoV-2 vaccines such as AstraZeneca's ChAdOx1 nCoV-19 have been associated with vaccine-induced thrombosis (TTS/VITT). We studied ChAdOx1 nCov-19 (AstraZeneca) and Ad26.COV2.S (Johnson & Johnson) and compared the vaccines using proteomics with mass spectrometric measurements. We cou...
ORGANISM(S): Homo sapiens (Human) 
2023-05-04 | PXD027344 | Pride
Ad26.cov2.s Sars-cov-2 Vector vaccines Chadox1 
ProteomicsProtein S-Nitrosylation of host and viral proteins upon fibroblast infection with Human Cytomegalovirus
Human Cytomegalovirus (HCMV) is a ubiquitous pathogen that has co-evolved with its host and in doing so, is highly efficient in undermining antiviral responses that limit successful infections. As a result, HCMV infections are highly problematic in individuals with weakened or underdeveloped immune ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-03 | PXD019208 | Pride
Hcmv Protein s-nitrosylation Cytomegalovirus 
ProteomicsEpigenetic resetting in the Parkinson's disease entail histone modification remodeling.
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons (DN) in the substantia nigra and disrupted cellular maintenance. Here, we demonstrate that NDST3-mediated epigenetic reprogramming halts neuronal degeneration and restores motor...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD067971 | Pride
Human Tmt Parkinson's Organoid Lc-ms/ms 
Sort   by:  
 Page size