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ProteomicsThe Hidden Culprit of Visceral Fat: Dysfunctional Subcutaneous Adipose Tissue – Serum proteomics
To investigate the proteomic profiles of paired subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) samples, as well as their correlations with clinical traits in severely obese patients, and to identify potential serum protein markers associated with tissue expression or metabolic s...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD041750 | Pride
Adipose tissue  visceral adipose tissue  subcutaneous adipose tissue  obesity  proteomics  type 2 diabetes  serum proteomics 
ProteomicsTobacco pollen tube-secretome following penetration through the pistil
As in animals, cell-cell communication plays pivotal role in male-female recognition during plant sexual reproduction. Prelaid peptides secreted from the female reproductive tissues guide pollen tubes towards ovules for fertilization. However, the elaborate mechanisms for this dialogue have remained...
ORGANISM(S): Nicotiana tabacum (Common tobacco) 
2016-03-18 | PXD002215 | Pride
Lc-msms Cell-cell communication Gel-free Label-free Nicotiana tabacum Pollen tube guidance Secretome 
ProteomicsLinezolid suppresses growth of tumours dervived from triple negative breast cancer, cancer chemoresistant and cancer stem-like cells through the induction of mitochondrial dysfunction
Cancer cells are known to reprogram their metabolism to adapt to adverse conditions dictated by tumor growth and microenvirontment. A subtype of cancer cells with stem-like properties, known as cancer stem cells (CSC) is thought to be responsible for tumour recurrence. These consequences are fatal f...
ORGANISM(S): Homo sapiens (Human) 
2018-11-04 | PXD009442 | Pride
Autophagy Cancer stem cells Ros Cancer Therapy resistance Antibiotics Lc-ms/ms 
ProteomicsStructural Basis of βKNL2 Centromeric Targeting Mechanism and Its Role in Plant-Specific Kinetochore Assembly
Structural Basis of βKNL2 Centromeric Targeting Mechanism and Its Role in Plant-Specific Kinetochore Assembly
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-05-28 | PXD067361 | Pride
Arabidopsis thaliana Sumoylation Betaknl2 
ProteomicsRole of Nse1 subunit of SMC5/6 complex as a ubiquitin ligase
Structural Maintenance of Chromosomes (SMC) complexes - cohesin, condensin and SMC5/6 - are important for many aspects of the chromosomal organization. These complexes are composed of Smc and non-Smc element (Nse) subunits. The Nse1 subunit of SMC5/6 contains a variant RING domain, characteristic of...
ORGANISM(S): Homo sapiens (Human) Schizosaccharomyces pombe 927 
2022-01-24 | PXD029573 | Pride
Liquid chromatography Mass spectrometry Ubiquitination Smc5/6  nse1 Ubiquitin ligase 
ProteomicsThe Hidden Culprit of Visceral Fat: Dysfunctional Subcutaneous Adipose Tissue – Adipose tissue proteomics
To investigate the proteomic profiles of paired subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) samples, as well as their correlations with clinical traits in severely obese patients, and to identify potential serum protein markers associated with tissue expression or metabolic s...
ORGANISM(S): Homo sapiens (Human) 
2023-10-16 | PXD041721 | Pride
Adipose tissue  visceral adipose tissue  subcutaneous adipose tissue  obesity  proteomics  type 2 diabetes 
UnknownQuantitative proteomics of the tobacco pollen tube secretome identifies novel pollen tube guidance proteins important for fertilization.
Not available
S-EPMC4853860 | biostudies-literature
ProteomicsA SMG7-eIF4A module constitutes a homeostatic system for P-bodies and Meiotic bodies
The nucleation of RNP granules requires the participation of mRNAs, which simultaneously as becoming their target, dictate their properties. Here we report that in Arabidopsis the RNA helicase eIF4A limits the condensation of P-bodies acting as an RNA chaperone, disassembled from the eIF4F complex. ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-03-25 | PXD061406 | Pride
Eif4a Stress granules P-bodies Eif4f Rnp granules Biomolecular condensates Smg7 Rna condensation Meiosis Meiotic bodies 
ProteomicsNovel phosphorylation substrates reveal a spatially regulated role for AAK1 in cell migration - SILAC proteome profiling to determine the impact of acute AAK1/BMP2K inhibition
NAKs (Numb-associated kinases) are a relatively unexplored kinase family that interacts with the endocytic machinery. Among NAK members, AAK1 has been linked to disorders such as neuropathic pain, schizophrenia, and Alzheimer's disease. Our goal is to better understand the cellular pathways regulate...
ORGANISM(S): Homo sapiens (Human) 
2026-03-19 | PXD055851 | Pride
Focal adhesions Lc-ms Silac Aak1 Migration Dda Bmp2k 
ProteomicsNovel phosphorylation substrates reveal a spatially regulated role for AAK1 in cell migration - LFQ proteome profiling to determine the impact of AAK1/BMP2K perturbation
NAKs (Numb-associated kinases) are a relatively unexplored kinase family that interacts with the endocytic machinery. Among NAK members, AAK1 has been linked to disorders such as neuropathic pain, schizophrenia, and Alzheimer's disease. Our goal is to better understand the cellular pathways regulate...
ORGANISM(S): Homo sapiens (Human) 
2026-03-19 | PXD055831 | Pride
Focal adhesions Lc-ms Dia Aak1 Lfq Migration Bmp2k 
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