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The objective of the study was to identify the fertility-associated metabolites in bovine spermatozoa using liquid chromatography-mass spectrometry (LC-MS). Six Holstein Friesian crossbred bulls (three high-fertile and three low-fertile bulls) were the experimental animals. Sperm proteins were isola...
2021-12-07 | MTBLS1071 | MetaboLights
The hypothalamus is an anatomically small, but functionally crucial region of the human brain. Normal hypothalamus functioning is central to the regulation of neuroendocrine and neurovegetative systems as well as modulation of chronobiology and behavioral aspects of the human body. Till date the hum...
ORGANISM(S): Homo sapiens (Human) 
2021-11-01 | PXD026879 | Pride
Gastric cancers (GCs) are often diagnosed in advanced stages, owing to non-specific clinical symptoms at early stages that resemble Acid Peptic Diseases (APDs). Despite recent efforts, a simple, liquid biopsy-based, multi-protein panel pre-diagnostic assay that can differentiate GCs from APDs is lac...
ORGANISM(S): Homo sapiens (Human) 
2025-09-18 | PXD064371 | Pride
Mycobacterium avium is one of the prominent disease causing bacteria in humans. It causes lymphadenitis, chronic pulmonary and extrapulmonary and disseminated infections in adults, children and immunocompromised humans. M. avium has ~4,500 predicted gene models, out of which not all are identified a...
ORGANISM(S): Mycobacterium avium 104 
2023-03-17 | PXD032067 | Pride
Interleukin-33 (IL-33) is a member of the IL-1 family of cytokines that play a central role in the regulation of immune responses. IL-33 signaling, from the early signaling events triggered by the ligand-activated receptor to result in activation of early and late signaling events, such as proteome...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD024385 | Pride
Oral cancer is the leading cancer worldwide with significant morbidity and mortality rate. Use of tobacco in form of both chewing and smoking have been known as major risk factors along with alcohol and HPV infection. Despite such knowledge, there are yet no proper screening strategy employed for sc...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD019014 | Pride
The incidence of sub-fertility is higher in crossbred bulls compared to zebu bulls. In the present study, we analysed the metabolomic profile of seminal plasma from crossbred and zebu bulls and uncovered differentially expressed metabolites between these two breeds. Using a high-throughput LC-MS/MS-...
2021-12-22 | MTBLS1642 | MetaboLights
Fat body is an important tissue in the context of vitellogenesis, vector immunity, vector physiology and vector-parasite interaction. However, the proteome of this vital organ has not been investigated in any Anopheline species so far. In this study, we employed multiple fractionation method followe...
ORGANISM(S): Anopheles stephensi (Asian malaria mosquito) 
2019-01-07 | PXD006677 | Pride
Mycobacterium tuberculosis, the causative agent of tuberculosis accounts for 1.5 million annual deaths worldwide. The two well-characterized strains of the parental H37 strain namely, H37Ra and H37Rv show different pathogenic phenotypes. In order to identify factors that are responsible for virulenc...
ORGANISM(S): Mycobacterium tuberculosis 
2017-05-08 | PXD004161 | Pride
The PRIDE ID's used for building the spectral library are PXD001188, PXD004161, PXD006039, PXD006117, PXD008555, PXD009549, respectively. The spectral library was created using the Bibliospec tool (version 1.0) with the .msf files generated from the total proteome search. The output files (.blib) we...
ORGANISM(S): Mycobacterium Tuberculosis H37rv (ncbitaxon:83332) 
2021-10-27 | MSV000088270 | MassIVE
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