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ProteomicsPerformance evaluation of the Q Exactive HF-X for shotgun proteomics
Performance evaluation of the Q Exactive HF-X for shotgun proteomics
ORGANISM(S): Homo sapiens (Human) 
2017-11-30 | PXD006932 | Pride
Q exactive hf-x bottom-up shotgun proteomics q exactive dia dda 
MetabolomicsGut metabolomics of 6PPD-Q exposed mice with ABX treatment

Untargeted fecal metabolomics using UHPLC-MS/MS to analyze microbiota-dependent metabolic changes in C57BL/6 mice exposed to 6PPD-quinone (6PPD-Q) with/without antibiotic-mediated gut microbiota depletion. Key pathways include tryptophan and nicotinamide metabolism linked to intestinal barrier fu...

2026-09-15 | MTBLS14308 | MetaboLights
MetabolomicsUntargeted LC-MS metabolomics of in vitro cultured Rothia mucilaginosa supernatant and pellet samples
This study reports untargeted LC-MS metabolomics data from in vitro culture of Rothia mucilaginosa (BNCC363031). A total of 13 biological samples were analyzed, including culture supernatant samples (S1-S5), bacterial pellet samples (B1-B5), and uninoculated medium controls (M1-M3). Data were acquir...
2026-10-06 | MTBLS14792 | MetaboLights
Metabolomicsliquid chromatography-mass spectrometry
Bacterial cells harvested at peak enzyme activity were subjected to untargeted metabolomic profiling to evaluate metabolic changes during straw degradation compared to control (CK) groups. Samples were extracted using pre-chilled methanol–water (4:1, v/v) and analyzed on a UHPLC-Q Exactive HF-X syst...
2026-08-24 | MTBLS15412 | MetaboLights
MetabolomicsRole and Mechanism of SERPINA1/PLG/TGFB1-Induced Adipose Fibroblast Activation in Dorsal Cervical Adipose Accumulation
This untargeted metabolomics study investigates metabolic differences in human adipose tissue between Group A (n=7) and Group B (n=7). Samples were analyzed using LC-MS/MS in both positive and negative ion modes on a Thermo Q-Exactive HF-X mass spectrometer. A total of 2,305 metabolites were detecte...
2026-05-08 | MTBLS14456 | MetaboLights
ProteomicsHuman_Testis_QE-HF - Deep Coverage Proteomics Identifies More Low-Abundance Missing Proteins in Human Testis Tissue with Q-Exactive HF Mass Spectrometer
The Chromosome-Centric Human Proteome Project (C-HPP) aims at finding existence evidence of missing proteins (MPs) at the early stage. Based on previous research, it has been proved that human testis tissue is suitable for further research of MPs because of its high gene expression level and high tr...
ORGANISM(S): Homo sapiens (Human) 
2016-09-30 | PXD004092 | Pride
Human Qe-hf Testis 
ProteomicsHow blood matrices and sample preparation can influence blood marker discovery
While plasma and serum are increasingly being studied by using high throughput proteomics, it remains largely unexplored how different types of blood materials collected in the routine clinical diagnostics laboratories influence protein marker discovery. We compared the LC-MS/MS proteomic profiles o...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD066304 | Pride
Plasma Speed Mass spectrometry Enrich-ist Serum Lc−ms Ist R package mpwr Data-independent acquisition Perca Mag-net 
ProteomicsHost and Bacterial Urine Proteomics Might Predict Treatment Outcomes for Immunotherapy in Advanced NSCLC
Urine extracellular vesicles from NSCLC patients were analyzed via LC-MS/MS to identify host and microbial proteins associated with progression-free survival. The study included 33 baseline urine samples and follow-up data. Samples were processed using EVtrap and analyzed on a Q-Exactive HF-X using ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-10 | PXD062630 | Pride
Urine Proteomics Nsclc Lc-ms Extracellular vesicles Immunotherapy Host-microbiome 
ProteomicsPeptidome in Chouguiyu at different fermentation time
Peptidome in Chouguiyu after fermentation for 0,4,and 8d using Easy-nLC 1200 UPLC-Q Exactive HF-X tandem mass.
ORGANISM(S): Siniperca chuatsi 
2022-10-15 | PXD033251 | Pride
Peptides Chouguiyu Lc-ms/ms 
MetabolomicsMetabolic and gut microbial remodeling in captive Amur tigers under uniform feeding

Ultra-high-performance liquid chromatography (UHPLC) was conducted using a Vanquish UHPLC system (Thermo Fisher), coupled with a Q Exactive™ HF/Q Exactive™ HF-X mass spectrometer for liquid chromatography-mass spectrometry (LC-MS) analysis. To ensure...

2026-06-05 | MTBLS14159 | MetaboLights
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