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ProteomicsFunction of CK2 selectively affects the endoplasmic reticulum and the Golgi apparatus in mTOR-mediated autophagy induction.
Selective autophagy of the endoplasmic reticulum, known as ER-phagy, is essential to maintain ER homeostasis. We recently showed that members of the autophagy receptor family FAM134 are regulated by phosphorylation-dependent ubiquitination. In an unbiased screen we had identified several kinases dow...
ORGANISM(S): Homo sapiens (Human) 
2025-03-07 | PXD049341 | Pride
Human Multiplexed Lc-ms Tmtpro 18plex Gprc Compounds 
ProteomicsThe function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways.
Selective autophagy of the endoplasmic reticulum (ER), known as ER-phagy, is an important regulator of ER remodeling and is critical to maintaining cellular homeostasis during environmental changes. We recently showed that members of the FAM134 family play a role during stress-induced ER-phagy. How...
ORGANISM(S): Homo sapiens (Human) 
2023-11-16 | PXD043003 | Pride
Ck2 Er homeostasis Lysosomal degradation Er remodeling Er fragmentation Chek1 Atr Selective autophagy Atm Ubiquitination. Stress response Fam134b Fam134c Endoplasmic reticulum Mtor 
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