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UnknownComparing the antidiabetic effects and chemical profiles of raw and fermented Chinese Ge-Gen-Qin-Lian decoction by integrating untargeted metabolomics and targeted analysis.
Not available
S-EPMC6204051 | biostudies-literature
UnknownA Study on the Therapeutic Efficacy of San Zi Yang Qin Decoction for Non-Alcoholic Fatty Liver Disease and the Underlying Mechanism Based on Network Pharmacology.
Not available
S-EPMC7810527 | biostudies-literature
UnknownAccurate Identification of Degraded Products of Aflatoxin B1 Under UV Irradiation Based on UPLC-Q-TOF-MS/MS and NMR Analysis.
Not available
S-EPMC8654243 | biostudies-literature
ProteomicsIntracellular proteins adsorbed on AuNPs during transcytosis and exocytosis
we set protein corona as the research object in this study, and focused on exploring the biological effects of intracellular protein corona (IPC) that formed on particle surface after transcytosis of nanomedicines. Considering the multi-functionalization characteristic, gold nanoparticles (AuNPs) we...
ORGANISM(S): Homo sapiens (Human) 
2020-01-20 | PXD015651 | Pride
Transcytosis Exocytosis Protein corona Caco-2 Aunps 
ProteomicsPotential proteins interated with CHRONO in human U2OS cells
We screened the protein partners that associate with CHRONO using immunoprecipitation followed with mass spectrometry (IP-MS). IP-MS identified proteins involved in multiple protein-protein interaction networks that are functional in multiple pathways and cellular functions.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD046945 | Pride
U2os cell Ip-ms Chrono 
MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
ProteomicstRF-22 RNA pulldown and Co-IP followed by LC-MS/MS in human cell samples
tRNA-derived fragments (tRFs) play a crucial role in tumor progression. However, whether and how tRFs regulate the immune response in esophageal squamous cell carcinoma (ESCC) and their potential clinical applications remain unclear. tRF-22 enhances myeloid-derived suppressor cells (MDSCs) infiltrat...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD057698 | Pride
Human Cell Trf-22 Escc Lc-ms/ms 
ProteomicsA proteomic landscape of diffuse-type gastric cancer
Here we present a dataset from 84 DGC patients with paired tumor and nearby tissue. Tumors and their nearby tissues were evaluated by pathologists. Nearby tissues were designated as non-cancerous and were greater than 5 cm away from the surgery margin. Hematoxylin and eosin (H&E) stained sections we...
ORGANISM(S): Homo sapiens (Human) 
2018-02-09 | PXD008840 | Pride
Gastric cancer Proteome 
ProteomicsChemoproteomic profiling of O-GlcNAcylated proteins and identification of O-GlcNAc transferases in rice
O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) is a ubiquitous posttranslational modification occurring in both animals and plants. Thousands of proteins along with their O-GlcNAcylation sites have been identified in various animal systems, yet the O-GlcNAcylated proteomes in plants remain po...
ORGANISM(S): Oryza sativa (Rice) 
2023-05-10 | PXD036527 | Pride
O-glcnacylation Hcd pd ethcd Metabolic glycan labeling Plant glycobiology. Rice Chemoproteomic 
MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Untargeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights
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