Sort   by:  
 Page size 
UnknownDietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer.
Not available
S-EPMC5511264 | biostudies-literature
UnknownA putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway.
Not available
S-EPMC4747185 | biostudies-literature
UnknownStructural rearrangements generate cell-specific, gene-independent CRISPR-Cas9 loss of fitness effects.
Not available
S-EPMC6362594 | biostudies-literature
ProteomicsComprehensive selectivity profile of PARP inhibitors using a target-centric bead matrix
Explore selectivity of several PARP inhibitors against proteins of the PARP family.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044329 | Pride
Niraparib Parp Talazoparib Olaparib 
UnknownUnsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting.
Not available
S-EPMC6088408 | biostudies-literature
ProteomicsOff-target profiling of several PARP inhibitors using immobilized Niraparib beads
Explore additional off-targets of several PARP inhibitors using Niraparib beads
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044330 | Pride
Niraparib Parp Talazoparib Olaparib 
ProteomicsComprehensive selectivity profile of PARP inhibitors using kinobeads
Explore kinase off-targets of several PARP inhibitors using kinobeads
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD045297 | Pride
Kinobeads Niraparib Parp Talazoparib Olaparib 
ProteomicsDetermine PARP1 and PARP2 target engagment of Niraparib and Olaparib in live cells
Determine the target engagment of PARP inhibitors (Niraparib and Olaparib) to PARP1 and PAPR2 in live cells using isothermal dose-response experiments
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD044332 | Pride
Parp2 Parp1 Tpp Niraparib Itdr Olaparib 
ProteomicsLive cell tracking of Niraparib off-targets using photo affinity labelling
Explore off-targets of Niraparib in live cells using photo affinity labelling (PAL)
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044331 | Pride
Pal Niraparib Parp Olaparib 
ProteomicsOff-target profiling of Niraparib and Olaparib using Thermal Proteome Profiling
Explore off-targets of Niraparib and Olaparib using 2D Thermal Proteome Profiling (2D-TPP)
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044334 | Pride
Thermal proteome profiling Parp Niraparib 2d-tpp Olaparib 
Sort   by:  
 Page size