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ProteomicsHuman Brain LC-MS/MS
Brian Protein Deamidation Associated with Amyloidosis Revealed by Soluble and Amyloidal Brian Proteome Profiling
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080692 | MassIVE
ProteomicsIn vivo murine brain protein synthesis uncover the molecular physiological process in brain
Identification of proteins that are synthesised de novo in response to specific microenvironmental cues is critical for understanding the molecular mechanisms, which underpin vital physiological processes and pathologies. Here, we report that a brief period of pulsed SILAM (Stable Isotope Labeling o...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-23 | PXD013502 | Pride
Pulsed silam Psivom Brain physiology Actively translating protein 
ProteomicsLACI Plasma Microvesicle Biomarker
The data are collected in triplicate from purified plasma microvesicles of LACI patient and matched control. the data were generated from a QStar Elite LC-MS/MS
ORGANISM(S): Homo sapiens (Human) 
2014-08-07 | PXD000748 | Pride
Laci stroke Exosome Plasma microvesicle 
ProteomicsGamma ray irradiation of epithelial carcinoma cells under hypoxic conditions
We demonstrate for the first time that under hypoxic conditions, A431 epithelial carcinoma cells exhibit increased viability when exposed to low-dose γ-irradiation, indicating that radiotherapy can promote tumor cell survival when oxygen supply is limited. When assessed using iTRAQ quantitative prot...
ORGANISM(S): Homo sapiens (Human) 
2017-02-27 | PXD003937 | Pride
Cancer Hypoxia Itraq Radiotherapy Calcium signaling pathway 
ProteomicsReticulocytes vs mature red blood cell
comparative study reticulocytes vs mature red blood cell
ORGANISM(S): Homo sapiens (Human) 
2017-11-09 | PXD003851 | Pride
Reticulocytes Mature red blood cell Malaria Itraq 
ProteomicsGamma ray irradiation of epithelial carcinoma cells under hypoxic conditions
We demonstrate for the first time that under hypoxic conditions, A431 epithelial carcinoma cells exhibit increased viability when exposed to low-dose ?-irradiation, indicating that radiotherapy can promote tumor cell survival when oxygen supply is limited. When assessed using iTRAQ quantitative prot...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080784 | MassIVE
ProteomicsVascular bed systematic profiling unravels endothelial and glycocalyx dysregulations in experimental high salt hypertension
Objective: Considerable evidence links dietary salt intake with the development of hypertension, left ventricular hypertrophy, and increased risk of stroke and coronary heart disease. Despite extensive epidemiological and basic science interrogation of the relationship between high salt (HS) intake ...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD031228 | Pride
Cardiovascular disease  endothelial cell dysfunction  glycocalyx  high salt diet  hypertension  mass spectrometry  proteomics   
ProteomicsEvaluation of the Effect of Trypsin Digestion Buffers on Artificial Deamidation
This work comprehensively compared 50 mM of ammonium acetate (pH 6), Tris-HCl (pH 8), ABC and TEAB as in-solution trypsin digestion buffers. Both iTRAQ quantification and label-free results indicate that ammonium acetate (pH 6) is more suitable than other buffers for studying endogenous deamidation ...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-28 | PXD001650 | Pride
Rat Kidney Artificial deamidation 
ProteomicsHuman Brain LC-MS/MS - Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissues
Brian Protein Deamidation Associated with Amyloidosis Revealed by Soluble and Amyloidal Brian Proteome Profiling
ORGANISM(S): Homo sapiens (Human) 
2016-08-24 | PXD002516 | Pride
Neurodegenerative disease Amyloids Deamidation Brain proteome 
ProteomicsA quantitative proteomic based approach to study the genistein induced epigenetic reprogramming in MDA-MB231 cells
Epidemiological data indicate that consumption of soy-based food significantly reduces the cancer risk in human through interaction with estrogen receptors and the ‘phytoestrogen’ genistein present in the soy is responsible for this chemopreventive activity. The epigenome regulatory effect of genist...
ORGANISM(S): Homo sapiens (Human) 
2018-07-05 | PXD006178 | Pride
Epigenome Epigenetics Dna repair Tmt Genistein Chromatome Heterochromatin Epigenetic reprogram Euchromatin Quantitative proteomics Chromatin 
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