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ProteomicsMouse,GC-1,TMT（Tandem Mass Tag）tag quantification
Tandem Mass Tag (TMT) technology is an in vitro peptide labeling technique developed by Thermo Fisher Scientific, a peptide labeling technology developed in vitro. The technology uses six (TMTsixplex™ Isobaric Label Reagent Set) or 10 (TMT10plex™ Isobaric Label Reagent Set) isotope labels by labelin...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-19 | PXD030967 | Pride
Gc-1 Mouse 
ProteomicsSLAPSHOT reveals rapid dynamics of extracellularly exposed proteome in response to calcium-activated plasma membrane phospholipid scrambling
To facilitate our understanding of the often rapid and nuanced dynamics of extracellularly exposed proteomes during signaling events, it is important to devise robust workflows affording fast time resolution without biases and confounding factors. Here, we present Surface-exposed protein Labeling u...
ORGANISM(S): Homo sapiens (Human) 
2024-08-29 | PXD041387 | Pride
Calcium signaling Surface proteomics Lc-msms Isobaric labeling Phospholipid scrambling 
ProteomicsAn isobaric labeling approach to enhance detection and quan-tification of tissue-derived plasma proteins as potential early disease biomarkers
Accurate detection and quantification of low abundance proteins by standard mass spectrometry approaches remains challenging. In addition, it is difficult to link low abundance plasma proteins back to their specific tissues or organs of origin with confidence. To address these challenges, we develop...
ORGANISM(S): Papio anubis anubis Papio hamadryas adenovirus 1 
2023-03-11 | PXD039430 | Pride
Lc-msms Kidney Tmt Plasma 
ProteomicsProteogenomic analysis of magnesium stress on cellulase activity in Bacillus licheniformis YNP5-TSU from biofilm associated proteins_sample13
During second generation biofuel production, optimization of cellulase activity is vital for synthesizing the end-product of anaerobic fermentation, bio-ethanol. The slightest change in pH, temperature, dissolved oxygen, carbon utilization, and addition or removal of essential supplements can reduce...
ORGANISM(S): Bacillus licheniformis 
2020-02-07 | PXD009275 | Pride
Bacillus Cellulase Biofilm Thermophiles Magnesium Yellowstone national park 
UnknownQuantitative Proteomics of Synaptosomal Fractions in a Rat Overexpressing Human DISC1 Gene Indicates Profound Synaptic Dysregulation in the Dorsal Striatum.
Not available
S-EPMC5808171 | biostudies-literature
ProteomicsHiRIEF Proteomics of Arabidopsis thaliana Col-0 and CIAF1 mutants
The assembly of the mitochondrial Complex I requires the expression of nuclear and mitochondrial located genes, co-factor biosynthesis and the assembly of at least 44 subunits. This requires the involvement of assembly factors that interact with subunits of Complex I but are not part of the final ho...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-10-08 | PXD011795 | Pride
Arabidopsis thaliana Salk_143656 Mitochondria Tim23 Complex i At1g76060 Hirief Ciaf1 Col-0 
ProteomicsCharting the dynamic trophoblast plasma membrane identifies LYN as a functional regulator of syncytialization
The differentiation of placental cytotrophoblasts (CTBs) into the syncytiotrophoblast (STB) layer results in significant remodeling of the plasma membrane proteome. Here, we use a peroxidase-catalyzed proximity labeling strategy to quantitatively map the dynamic plasma membrane proteomes of CTBs and...
ORGANISM(S): Homo sapiens (Human) 
2025-10-02 | PXD052032 | Pride
Trophoblast Plasma membrane Proximity labeling Syncytialization 
ProteomicsA ubiquitin-specific, proximity-based labeling approach for the identification of ubiquitin ligase substrates
Ubiquitination of proteins is central to protein homeostasis and other cellular processes including DNA repair, vesicular transport, cell-division etc. The process of ubiquitination is conserved from yeast to humans and is carried out by the sequential action of three enzymes: E1, E2 and E3. There ...
ORGANISM(S): Homo sapiens (Human) 
2024-11-26 | PXD045521 | Pride
Bira Substrate identification U box Ring E3 ligase Ubiquitin 
ProteomicsComparative analysis of intra- and extracellular vesicles from cytotoxic CD8+ αβ T cells and γδ T cells
Although belonging to different branches of the immune system, cytotoxic CD8+ αβ T cells and γδ T cells utilize common cytolytic effectors including FasL, granzymes, perforin and granulysin. The effector proteins are stored in different subsets of lysosome-related effector vesicles (LREVs) and relea...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055377 | Pride
Exosomes Lysosome-related effector vesicles (lrevs) Cd8+ t cells Αβ t cells Cytotoxic granules Cytotoxic effector proteins Γδ t cells Cytotoxic t cells Proteomic profiling Extracellular vesicles (evs) 
ProteomicsAspergillus oryzae LC-MSMS - Comparative proteomic analysis: SclR is importantly involved in carbohydrate metabolism in Aspergillus oryzae
We previously identified the bHLH transcription factor SclR and found that the loss of SclR function led to significant phenotypic changes, such as rapid protein degradation and cell lysis in dextrin-polypeptone-yeast extract liquid medium. Therefore, this study presents a comparative assessment at ...
ORGANISM(S): Aspergillus oryzae RIB40 
2017-11-07 | PXD007829 | Pride
Lc-msms Bhlh Aspergillus oryzae 
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