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UnknownLYTACs that engage the asialoglycoprotein receptor for targeted protein degradation.
Not available
S-EPMC8387313 | biostudies-literature
UnknownLigand conjugate SAR and enhanced delivery in NHP.
Not available
S-EPMC8531135 | biostudies-literature
UnknownDevelopment of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins.
Not available
S-EPMC8006166 | biostudies-literature
UnknownLiver-targeted degradation of BRD4 reverses hepatic fibrosis and enhances metabolism in murine models.
Not available
S-EPMC12315693 | biostudies-literature
Unknown<sup>68</sup>Ga-Labeled Glycopeptides as Effective Tools for Liver Function Imaging.
Not available
S-EPMC11881035 | biostudies-literature
UnknownHarnessing Bone-Liver Crosstalk: A Dual-Action LYTAC Approach for Bone-Specific Accumulation and Liver-Specific Protein Degradation in Bone Disorders.
Not available
S-EPMC12728634 | biostudies-literature
UnknownsiRNAs containing 2'-fluorinated Northern-methanocarbacyclic (2'-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2'-F-NMC NTPs.
Not available
S-EPMC7969009 | biostudies-literature
UnknownNon-Covalent Linkage of Helper Functions to Dumbbell-Shaped DNA Vectors for Targeted Delivery.
Not available
S-EPMC9962178 | biostudies-literature
ProteomicsGlycan-based Biological Degraders Targeting the Cytokine Immune Axis
The project investigates targeted degradation of IL-6 and sIL6-R using bispecific Biological Degraders (BioDegs) that enable receptor-mediated uptake via the asialoglycoprotein receptor (ASGPR). Various IL-6(R)–binding scaffolds were modified with triantennary N-acetylgalactosamine (TGN) to promote ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-17 | PXD075514 | Pride
Asgpr Targeted protein degradation Biological degraders Tri-n-acetylgalactosamine Lysosomal degradation Il-6 Sil-6r 
UnknownAn innovative immunotherapeutic strategy for ovarian cancer: CLEC10A and glycomimetic peptides.
Not available
S-EPMC5905120 | biostudies-literature
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