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Pancreatic ductal adenocarcinoma (PDAC), with its devastating prognosis and limited treatment options, necessitates innovative therapeutic strategies. T-cell-based immunotherapy has shown promise for various cancers, including PDAC. Thus, a comprehensive understanding of the HLA-peptidome in PDAC is...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD054417 | Pride
Pancreatic ductal adenocarcinoma (PDAC), with its devastating prognosis and limited treatment options, necessitates innovative therapeutic strategies. T-cell-based immunotherapy has shown promise for various cancers, including PDAC. Thus, a comprehensive understanding of the HLA-peptidome in PDAC is...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD054360 | Pride
Acute respiratory distress syndrome (ARDS) is associated with a substantial burden of morbidity and mortality. Prior studies have identified reproducible hyperinflammatory and hypoinflammatory ARDS subphenotypes with distinct clinical outcomes and treatment responses. Although recent transcriptomic ...
ORGANISM(S): Homo sapiens (Human) 
2026-10-02 | PXD079948 | Pride
Alveolar macrophages play a pivotal role in maintaining pulmonary homeostasis. While their primary function is the phagocytic clearance of xenobiotic substances, our recent studies have demonstrated that they also possess a mechanism for the active uptake of bacterial-derived peptides through peptid...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-07-04 | PXD066610 | Pride
Progressive supranuclear palsy (PSP) is a tauopathy that presents region-specific patterns of neurodegeneration, affecting cortical and subcortical areas with relative selectivity. Among these, the anterior cingulate cortex (ACC) is of particular interest due to its involvement in executive function...
ORGANISM(S): Homo sapiens (Human) 
2026-05-19 | PXD066064 | Pride
Background: Synaptic transmission and network activity rely on high ATP turnover. Impairments in cerebral energy metabolism are increasingly recognized as central to aging and the pathogenesis of Alzheimer’s disease (AD). AD is related to elevated risk for perioperative neurological complications, i...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD072113 | Pride
Telomeric sequences vary across the tree of life and intimately co-evolve with telomere-binding protein complexes. However, the molecular mechanisms allowing organisms to adapt to new telomeric sequences are difficult to gauge from extant species. Here, we reprogrammed multiple yeast lines to human-...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-02-19 | PXD064562 | Pride
A dataset of nine diverse yeast species cultivated in different media.
ORGANISM(S): Candida albicans (Yeast) Kluyveromyces lactis Komagataella phaffii Saccharomyces cerevisiae BY4741 Kluyveromyces marxianus Lachancea thermotolerans Wickerhamomyces anomalus Candida tropicalis CAB54-6763-3 
2025-07-04 | PXD064343 | Pride
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