Sort   by:  
 Page size 
ProteomicsIdentification of RPA1 interactome in mouse liver tissue
To examine the molecular mechanisms by which RPA1 regulates transcription in liver, we conducted immunoprecipitation followed by mass spectrometry to characterize RPA1-associated proteins in mouse liver.
ORGANISM(S): Mus musculus (Mouse) 
2022-07-19 | PXD021529 | Pride
Mouse liver Rpa1 Interactome 
ProteomicsDUSP2 dephosphorylates STAT3 at Y705 and S727 residues
In the related study, to determine whether DUSP2 definitively served as a phosphatase for STAT3, an in vitro phosphatase assay was used. Using S-tag beads, p-STAT3 was pulled down from IL-6 stimulated HEK293T cells transfected with STAT3-S-Tag. DUSP2 or control protein, which was purified from HEK29...
ORGANISM(S): Homo sapiens (Human) 
2015-10-13 | PXD002743 | Pride
Dusp2 Phosphorylation Stat3 
ProteomicsIdentification of PAC1 interactome in activated T cells
To examine the molecular mechanisms by which PAC1 suppresses T cell response to antigen, we conducted immunoprecipitation followed by mass spectrometry to characterize PAC1-associated proteins in activated T cells
ORGANISM(S): Homo sapiens (Human) 
2020-01-07 | PXD012201 | Pride
Pac1 T cells Interactome 
ProteomicsLC-MS/MS analysis of B12 treated SH-SY5Y cells
B12 is a compound that has neuroprotective effects. We investigated the protein expression profile associated with the neuroprotective effects of B12 on human neuronal cells SH-SY5Y using label-free quantitative proteomics.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-12-29 | MSV000079437 | MassIVE
ProteomicsSTN1 facilitates metastasis by promoting transcription of EMT-activator ZEB1 in pancreatic cancer
As pancreatic ductal adenocarcinoma (PDAC) poses a formidable clinical challenge, demanding further exploration of its pathogenesis and drugs targeted for metastasis-the main cause of mortality. Here, we identified STN1, a CST complex member crucial for maintaining telomere lengths and genome stabil...
ORGANISM(S): Homo sapiens (Human) 
2025-08-05 | PXD062518 | Pride
Pancreatic cancer  stn1  stat3 
UnknownNeurocognition as a major predictor of 8-week response to antipsychotics for drug-naive first-episode schizophrenia using machine learning.
Not available
S-EPMC12284124 | biostudies-literature
UnknownTrajectory analysis of BMI increase induced by second-generation antipsychotics in first-episode schizophrenia: a secondary analysis based on CNFEST***.
Not available
S-EPMC12783731 | biostudies-literature
ProteomicsIdentification of PTENα associated proteins under stress condictions in B16 cells by mass spectrometry
PTENα is the first isoform of tumor suppressor PTEN. To investigate the molecular mechanism by which PTENα modulates cell response to inflammation, we performed pull-down assays with FLAG-tagged proteins coupled with mass spectrometry under condition of H2O2 treatment in B16 cells.
ORGANISM(S): Mus Musculus 
2021-07-13 | PXD040709 |
ProteomicsIdentification of proteins affected by PTENα under stress conditions by mass spectrometry
Stress granules are known to be related with selective translation. To determine which proteins are regulated by stress granules assembly in Ptenα─/─ MEFs, we performed a mass spectrometry analysis of Ptenα+/+ and Ptenα─/─ MEFs under oxidative stress.
ORGANISM(S): Mus Musculus 
PXD021840 |
ProteomicsCOVID-19 increases extracorporeal coagulation during hemodialysis through upregulation of vWF/FBNL5 signaling
Introduction: COVID-19 has been shown to increase the risk of extracorporeal coagulation during hemodialysis in patients, but the mechanism is unclear. This study aims to investigate the effect and mechanism of COVID-19 on the risk of extracorporeal coagulation during hemodialysis. Methods: A retro...
ORGANISM(S): Homo Sapiens 
PXD044377 |
Sort   by:  
 Page size