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ProteomicsTMT-based Multiplexed (Chemo)proteomics on the Orbitrap Astral Mass Spectrometer
This dataset contains an evaluation of TMT-based multiplexed proteomics on the Orbitrap Astral mass spectrometer.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-12-17 | MSV000096674 | MassIVE
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer – REVISION
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2026-01-26 | PXD071972 | Pride
Astral Ms Orbitrap Zoom 
ProteomicsExpanding the global map of protein post translational modifications with PTMScan enrichment and nDIA analysis on the Orbitrap Astral
The study describes the use of PTMScan enrichment and LC-MS/MS analysis using Orbitrap Astral for the deep coverage of different PTM peptides from cells and tissue.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-05-21 | PXD065579 | Pride
Ubiquitination Succinylation Ptm Methylation Ptmscan Orbitrap astral Ndia Acetylation Mass spec Dda Phosphorylation 
ProteomicsData-independent proteomic profiling of Escherichia coli across graded 13C abundance treatments using Astral LC-MS/MS
This dataset contains data-independent acquisition (DIA) LC-MS/MS measurements of Escherichia coli samples acquired across a gradient of 13C abundance treatments. The treatment groups correspond to 1%, 2%, 5%, 25%, 50%, and 99% 13C abundance, with three replicate runs collected for each treatment le...
ORGANISM(S): Escherichia coli Bacteria 
2026-09-08 | PXD075964 | Pride
13c abundance Proteomics Dia Stable isotope probing Sip Escherichia coli Astral Evosep one Label-free Orbitrap Lc-ms/ms 
ProteomicsFelipe Sheep EV DIA LC/MS/MS using the Orbitrap Astral
DIA analysis of sheep EVs using Evosep one and Orbitrap Astral
ORGANISM(S): Ovis aries 
2026-09-14 | PXD077206 | Pride
Ev Dia Astral Sheep 
ProteomicsThe one hour human proteome: Orbitrap Astral Mass Spectrometer
We highlight the leap in performance made possible with new instrumentation in the Thermo Scientific Orbitrap Astral™ mass spectrometer. Integrated alongside a high-resolution accurate mass (HRAM) Orbitrap analyzer, the instrument introduces a fast-switching quadrupole mass filter congruent with dow...
ORGANISM(S): Homo sapiens (Human) 
2024-03-29 | PXD049028 | Pride
Proteomics Dia Orbitrap astral High-throughput 
UnknownQuantitative Label-Free Single-Cell Proteomics on the Orbitrap Astral MS.
Not available
S-EPMC12209951 | biostudies-literature
ProteomicsBreaking Barriers in Crosslinking Mass Spectrometry: Enhanced Throughput and Sensitivity with the Orbitrap Astral Mass Analyzer
Crosslinking mass spectrometry (XL-MS) has become a key technique for investigating protein-protein interactions and the architecture of biological systems. This study compares the Orbitrap Astral and Eclipse mass spectrometers in XL-MS workflows, emphasizing their performance in detecting low-abund...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD059096 | Pride
Crosslinking mass spectrometry Fragmentation Orbitrap eclipse Hcd Quality control Compensation voltage Orbitrap astral 
ProteomicsHigher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer -Tritation Injection time-Astral-
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD066927 | Pride
Injection time tritation Astral 
UnknownASTRAL: genome-scale coalescent-based species tree estimation.
Not available
S-EPMC4147915 | biostudies-literature
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