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Eurasian common shrews (Sorex araneus) maintain exceptionally high metabolic rates year-round, posing a significant energetic challenge during winter when food availability declines. To investigate seasonal metabolic regulation, we performed proteomic profiling of liver tissue—central to energy home...
ORGANISM(S): Sorex araneus 
2025-10-31 | PXD068559 | Pride
The joint disease rheumatoid arthritis (RA) is characterized by persistent synovitis, leading to cartilage damage, bone erosion, and ultimately impaired joint function. The disease affects 0.5 to 1.0% of adults in developed countries, and is three times more frequent in women than in men. A number o...
ORGANISM(S): Homo sapiens (Human) 
2016-09-26 | PXD003082 | Pride
Introduction Chlamydia trachomatis (C. trachomatis) is a Gram-negative bacterium and a common human pathogen. The World Health Organization (WHO) estimates that over 130 million people are infected with C. trachomatis globally each year and with increasing incidence. C. trachomatis causes long-lasti...
ORGANISM(S): Chlamydia trachomatis L2/434/Bu(f) Chlamydia trachomatis Homo sapiens (Human) Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) Chlamydia trachomatis L2/434/Bu(i) 
2020-11-23 | PXD019393 | Pride
The etiology of the inflammatory bowel diseases, including ulcerative colitis, remains incomplete, but recent findings points to the involvement of complex host-microbial interactions. We hypothesized that an analysis of the proteins on the host-microbial interacting surface, the intestinal mucosa, ...
ORGANISM(S): Homo sapiens (Human) 
2015-05-26 | PXD001608 | Pride
Introduction: Early life is characterized by heightened susceptibility to infections and is recognized as a major determinant of the immune system development and the overall health for the entire human lifespan. However, our knowledge of the development of the neonatal immune system is incomplete, ...
ORGANISM(S): Homo sapiens (Human) 
2020-11-24 | PXD019817 | Pride
Clinical proteomics research is in part limited by the availability of clinical samples. However, large biobanks exist worldwide containing formalin-fixed and paraffin embedded samples and samples stored in RNAlater. The extraction of proteins for proteome analysis from samples prepared by either me...
ORGANISM(S): Homo sapiens (Human) 
2015-11-23 | PXD002029 | Pride
Total pancreatectomy with islet cell autotransplantation (TPIAT) is a surgical treatment modality used for the management of painful chronic pancreatitis when medical and endoscopic therapies fail. Total pancreatectomy (TP) results in a number of clinical implications. However, the glucose-responsiv...
ORGANISM(S): Homo sapiens (Human) 
2022-08-19 | PXD028570 | Pride
We established a spectral library for data-independent analysis of human plasma samples, using a pooled plasma sample from Danish adults. The samples were prepared for proteome analysis using an in-house developed protocol consuming one microliter of plasma per sample, and the tryptic digest and sub...
ORGANISM(S): Homo sapiens (Human) 
2018-04-20 | PXD008163 | Pride
Clinical proteomics research is in part limited by the availability of clinical samples. However, large biobanks exist worldwide containing formalin-fixed and paraffin embedded samples and samples stored in RNAlater. The extraction of proteins for proteome analysis from samples prepared by either me...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080863 | MassIVE
The joint disease rheumatoid arthritis (RA) is characterized by persistent synovitis, leading to cartilage damage, bone erosion, and ultimately impaired joint function. The disease affects 0.5 to 1.0% of adults in developed countries, and is three times more frequent in women than in men. A number o...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080861 | MassIVE
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