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ProteomicsNative MS and intact-protein MS datasets for NreB and NreB_PAS supporting the study “A labile sulfur ligand in a three-cysteine-coordinated [2Fe-2S] cluster mediates sulfide sensing in NreB”
This ProteomeXchange dataset contains native mass spectrometry and intact-protein mass spectrometry data generated in support of the manuscript “A labile sulfur ligand in a three-cysteine-coordinated [2Fe-2S] cluster mediates sulfide sensing in NreB”. The dataset includes intact-protein MS measureme...
ORGANISM(S): Bacillus licheniformis DSM 13 = ATCC 14580 
2026-04-15 | PXD076861 | Pride
Nreb_pas Gsh Nreb Fe-s cluster Nahs Native ms Sulfide sensing Bruker impact hd [2fe-2s] Intact protein ms 
MetabolomicsCascading effects of root microbial symbiosis on the development and metabolome of the insect herbivore Manduca sexta L

Root mutualistic microbes can modulate the production of plant secondary metabolites affecting plant–herbivore interactions. Still, the main mechanisms underlying the impact of root mutualists on herbivore performance remain ambiguous. In particular, little is known about how changes in the plant...

2023-09-12 | MTBLS2700 | MetaboLights
ProteomicsTapered-tip Capillary Electrophoresis Nano-electrospray Ionization Mass Spectrometry for Ultrasensitive Proteomics: The Mouse Cortex
We have enabled ultrasensitive proteomics of limited protein digests by developing a tapered-tip nanoelectrospray ionization (nanoESI) interface for microanalytical capillary electrophoresis (CE) high resolution mass spectrometry (HRMS). CE-nanoESI-HRMS allowed us to detect 260 zmol angiotensin II (...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-18 | PXD005222 | Pride
Liquid chromatography Brain Capillary electrophoresis Mass spectrometry Bottom-up proteomics Mouse Nanoelectrospray ionization Impact hd 
ProteomicsLabel-free Quantification of Proteins in Single Embryonic Cells with Neural Fate in the Cleavage-Stage Frog (Xenopus laevis) Embryo using CE-ESI-HRMS
In this work, we integrate capillary electrophoresis electrospray ionization mass spectrometry, bottom-up proteomics, and single-cell microanalysis to enable the label-free quantification (LFQ) of proteins in single embryonic cells (D11 blastomeres) in the 16-cell frog (Xenopus laevis) embryo. Based...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2016-06-23 | PXD004174 | Pride
Blastomere Embryo Proteomics Xenopus Mass spectrometry Fusion Label free quantification Single cell Lfq Capillary electrophoresis Electrospray ionization Impact hd 
OtherCyanobacteria extracts and fractions - LC-MSMS
Cyanobacteria extracts and SPE fractions. LC MSMS analysis was performed in an UltiMate 3000 UPLC system (Thermo Scientific) using a Kinetex 1.7 mm C18 reversed phase UHPLC column (50 X 2.1 mm) and Maxis Impact HD Q-TOF mass spectrometer (Bruker Daltonics) equipped with ESI source.
ORGANISM(S): Cyanobacteria 
2019-10-10 | MSV000084447 | MassIVE
TranscriptomicsSurface topography guides morphology and spatial patterning of induced pluripotent stem cell colonies
The relevance of topographic cues for commitment of induced pluripotent stem cells (iPSCs) is largely unknown. In this study, we demonstrate that groove-ridge structures with a periodicity in the submicrometer range induce elongation of iPSC colonies, guide the orientation of apical actin fibers, an...
ORGANISM(S): Homo sapiens 
2018-10-31 | E-MTAB-7327 | biostudies-arrayexpress
MetabolomicsData processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online

Systems biology is the study of complex living organisms, and as such, analysis on a systems-wide scale involves the collection of information-dense data sets that are representative of an entire phenotype. To uncover dynamic biological mechanisms, bioinformatics tools have become essential to fa...

2017-11-23 | MTBLS572 | MetaboLights
ProteomicsData in support of TNF inhibition in experimental rotator cuff tear mouse model
Musculoskeletal injuries related to the rotator cuff (RC) are frequent and account for up to 70% of shoulder pain problems. Lesions of the RC lead to weakness and pain (ref: Carr et al mfl) and untreated these lesions are acompanied by muscle degeneration modulated by inflammatory reactions that var...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-12 | PXD035331 | Pride
Proteomics Rotator cuff Mouse 
ProteomicsHuman IgG1 (B-cell receptor) Fc peptide glycan analysis, LC-MS
Since few data are available on glycans expressed by human BCRs, we aimed to analyze the Fc glycans of membrane-bound IgG after BCR capture and tryptic digestion by LC-MS. For this purpose, human B-cell lines from Burkitt Lymphoma (Ramos) expressing IgG1-BCRs in the presence or absence of Fc glycans...
ORGANISM(S): Homo sapiens (Human) 
2023-12-11 | PXD047089 | Pride
Human B-cell receptor Igg1 fc peptide glycans Lc-ms 
ProteomicsHDX-MS analysis of p110a in complex with regulatory subunits
HDX-MS was used to map the changes in conformational dynamics in the catalytic subunit of PI3Ka, p110a, in complex with the following five reguatory subunits: p85a, p85b, p55g, p55a, p50a. Apo and pY activated states were also compared between the three splice variants encoded by PIK3R1. No signific...
ORGANISM(S): Homo sapiens (Human) 
2025-11-20 | PXD069057 | Pride
Hdx-ms Pi3ka P85 
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