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ProteomicsA Phosphotriester-Masked Dideoxy-cGAMP Derivative as a Cell-Permeable STING Agonist
2’3’-cyclic GMP-AMP (cGAMP) is a cyclic dinucleotide second messenger in which guanosine and adenosine are connected by one 3’-5’ and one 2’-5’ phosphodiester linkage. It is formed in the cytosol upon detection of pathogenic DNA by the enzyme guanosine-monophosphate-adenosine monophosphate synthase ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057395 | Pride
Sting Interferone Cgamp 
ProteomicsDevelopment of an sulfoxide-based, CuAAC-enrichable cross-linker
Cross-linking of BSA with a novel cross-linker. Modification of the cross-linker containing peptides with CuAAC-chemistry to attach a cleavable biotin-derivative. Enrichment with streptavidin-beads.
ORGANISM(S): Bos taurus (Bovine) 
2019-10-14 | PXD015080 | Pride
Cuaac Xl-ms Sulfoxide 
ProteomicsRedirected nuclear glutamate dehydrogenase supplies Tet3 with a-ketoglutarate in neurons
Tet3 is an Fe2+-dependent enzyme that oxidizes genomic 5-methylcytosine to 5-hydroxymethylcytosine with the help of alpha-ketoglutarate and oxygen. It is the most abundant Tet enzyme in differentiated tissues including brain. Adult brain contains the highest 5-hydroxymethylcytosine levels. How alpha...
ORGANISM(S): Mus musculus (Mouse) 
2021-05-10 | PXD004518 | Pride
Citric acid cycle Epigenetics Alpha-ketoglutarate Oxaloacetate Tet3 Isocitrate Hmc 
ProteomicsMm_mChmC_DynamicReader
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives
ORGANISM(S): Mus Musculus 
2013-12-31 | PAe004058 | PeptideAtlas
UnknownMethylprednisolone for Infant Heart Surgery: Subpopulation Analyses of a Randomized Controlled Trial.
Not available
S-EPMC12378003 | biostudies-literature
UnknownPersistent Imbalance: Women's Representation in North American Pediatric Cardiology Leadership Roles.
Not available
S-EPMC12418463 | biostudies-literature
UnknownEvaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection.
Not available
S-EPMC5853450 | biostudies-literature
UnknownClinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study.
Not available
S-EPMC6501846 | biostudies-literature
UnknownA multidisciplinary approach and consensus statement to establish standards of care for Angelman syndrome.
Not available
S-EPMC8922964 | biostudies-literature
UnknownInternational Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature.
Not available
S-EPMC9378753 | biostudies-literature
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