Sort   by:  
 Page size 
ProteomicsAG3C glucose starvation time course
This data set consists of a long term glucose starvation time course of E. coli grown in minimal media for up to two weeks. Unlike previous studies of long term starvation,Our study focuses on the physiological response of E. Coli in stationary phase as a result of being starved for glucose, not on ...
ORGANISM(S): Escherichia coli 
2015-08-24 | PXD002140 | Pride
Bacterial physiology Long term glucose starvation Multi-omic dataset 
TranscriptomicsIdentification of Common Genetic Variants that Account for Transcript Isoform Variation between Human Populations
In addition to the differences between populations in transcriptional and translational regulation of genes, alternative pre-mRNA splicing (AS) is also likely to play an important role in regulating gene expression and generating variation in mRNA and protein isoforms. Recently, the genetic contribu...
ORGANISM(S): Homo sapiens 
2010-08-19 | E-GEOD-9703 | biostudies-arrayexpress
UnknownPsychometric Evaluation of the Neuropsychological Test Battery in Individuals with Normal Cognition, Mild Cognitive Impairment, or Mild to Moderate Alzheimer's Disease: Results from a Longitudinal Study.
Not available
S-EPMC12280754 | biostudies-literature
ProteomicsHDX-MS analysis of NKp46 with next gen antibodies
Eptiopes of 7 unique antibodies produced by two complementary in vivo platforms utilizing a common light chain, in a chicken (OmniClic) or rat (OmniFlic) host species on NKp46 were analysed using HDX-MS. NKp46 was used as a model target antigen due to its use in emerging Natural Killer (NK) immune e...
ORGANISM(S): Homo sapiens (Human) 
2025-11-27 | PXD069455 | Pride
Epitope Antibody Nkp46 Hdx 
ProteomicsHDX-MS of TRAPPII reveals a conserved Rab binding interface
We used hydrogen deuterium exchange mass spectrometry (HDX-MS) to define the interface of TRAPPII with three Rab GTPases (Rab1, Rab11, Rab43). These experiments were performed in the presence of EDTA to generate a nucleotide free stabilised Rab-GEF complex. Significant decreases in deuterium incorpo...
ORGANISM(S): Homo sapiens (Human) 
2020-12-11 | PXD020890 | Pride
Hdx-ms Trappii Gef Rab 
ProteomicsStructure of the phosphoinositide 3-kinase p110-p101 complex reveals molecular mechanism of GPCR activation
The class IB phosphoinositide 3-kinase (PI3K), PI3K, is a master regulator of immune cell function, and is a promising drug target for both inflammatory diseases and cancer. Critical to PI3K function is the association of the p110 catalytic subunit to either a p101 or p84 regulatory subunit, which ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-22 | PXD025209 | Pride
Hdx Cryo-em Gpcr Pik3g 
ProteomicsCentral nervous system involvement of acute lymphoblastic leukemia depends on mRNA translation and complement component 3
Central nervous system (CNS) dissemination of B-precursor acute lymphoblastic leukemia (B-ALL) has a poor prognosis and remains a therapeutic challenge with few recent advances in therapy. Leptomeningeal disease is particularly common in the high risk subgroup of KMT2A-rearranged B-ALL (KMT2A-r B-AL...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD022411 | Pride
Lc-ms Leukemia Lfq 
ProteomicsHDX-MS analysis of p110a in complex with regulatory subunits
HDX-MS was used to map the changes in conformational dynamics in the catalytic subunit of PI3Ka, p110a, in complex with the following five reguatory subunits: p85a, p85b, p55g, p55a, p50a. Apo and pY activated states were also compared between the three splice variants encoded by PIK3R1. No signific...
ORGANISM(S): Homo sapiens (Human) 
2025-11-20 | PXD069057 | Pride
Hdx-ms Pi3ka P85 
UnknownPhase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Combination With Fludarabine and Cytarabine, in Pediatric Relapsed or Refractory Acute Leukemia.
Not available
S-EPMC5477824 | biostudies-literature
UnknownConsistent patterns of common species across tropical tree communities.
Not available
S-EPMC10808064 | biostudies-literature
Sort   by:  
 Page size