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TranscriptomicsCOX-2 network as predictive molecular marker for clinical pregnancy in IVF
CONTEXT Nowadays, the molecular mechanisms involved in endometrial receptivity and implantation are still not clear. OBJECTIVE The gene expression of human endometrium of patients undergoing an IVF treatment with GnRH antagonists/rec-FSH was studied. CONCLUSIONS COX-2 has been extensively studied ...
ORGANISM(S): Homo sapiens 
2010-09-06 | E-GEOD-18140 | biostudies-arrayexpress
ProteomicsProteomics analysis of Medulloblastoma
Medulloblastoma (MB) is the most common malignant brain tumor in children. It is a neuroectodermal tumor located in the cerebellum. International consensus recognizes four distinct subgroups of MBs including Wingless (WNT), Sonic Hedgehog (SHH), Group 3 (G3), and Group 4 (G4) with distinct molecular...
ORGANISM(S): Homo sapiens (Human) 
2025-12-11 | PXD053458 | Pride
Proteomics Multi-omics Cerebellum Medulloblastoma Metabolism. Pediatric brain tumor Phosphoproteomics 
ProteomicsPhosphoproteomics analysis of Medulloblastoma
Medulloblastoma (MB) is the most common malignant brain tumor in children. It is a neuroectodermal tumor located in the cerebellum. International consensus recognizes four distinct subgroups of MBs including Wingless (WNT), Sonic Hedgehog (SHH), Group 3 (G3), and Group 4 (G4) with distinct molecular...
ORGANISM(S): Homo sapiens (Human) 
2025-12-11 | PXD053675 | Pride
Proteomics Multi-omics Cerebellum Medulloblastoma Metabolism. Pediatric brain tumor Phosphoproteomics 
TranscriptomicsLow dose hCG pregnant vs non-pregnant
Influence of ovarian stimulation with 200 IU of hCG, (administered in the late follicular phase among ICSI patients undergoing a GnRH-antagonist protocol), on the endometrium on the day of oocyte pick-up. The purpose of the present study is to assess the influence of the administration of low dose h...
ORGANISM(S): Homo sapiens 
2010-09-07 | E-GEOD-21225 | biostudies-arrayexpress
ProteomicsUHMK1 is a novel splicing regulatory kinase
The U2AF Homology Motif Kinase 1 (UHMK1) is the only kinase that contains the U2AF homology motif (UHM), a common protein interaction domain among splicing factors. Through this motif, UHMK1 interacts with the splicing factors SF1 and SF3B1, known to participate in the 3’ splice site recognition and...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-02 | PXD033353 | Pride
Lc-msms Tmt6 Nih3t3 Phosphoproteomics Mouse 
ProteomicsGlucose modulates transcription factor dimerization to enable tissue differentiation
Glucose is a universal energy currency for living organisms, however, its non-energetic functions in processes such as differentiation are undefined. In epidermis, differentiating cells exhibit dynamic changes in gene expression1-4 driven by specific transcription factors (TFs)5-9. The interplay bet...
ORGANISM(S): Homo sapiens (Human) 
2025-03-13 | PXD038128 | Pride
Differentiation Metabolomics Glucose Irf6 
ProteomicsA feedback loop sustaining neutrophil extracellular trap formation involves S100 proteins, histones, TLR2 and RAGE, and is restrained by albumin
Neutrophil extracellular trap (NET) generation must be tightly controlled as this essential antimicrobial response can also cause tissue damage and contribute to various pathologies. We previously described that neutrophils undergoing NET formation release endogenous mediators that feed back on the ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD078688 | Pride
Tlr2 Endogenous factors Rage Histones Human serum albumin Neutrophil extracellular traps S100 proteins Damps 
TranscriptomicsGBM-Space: Joint Transcriptome and Chromatin Accessibility Profiling of Glioblastoma (10x Genomics - Multiome)
Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single cell and spatial multi-omic a...
ORGANISM(S): Homo sapiens 
2026-09-12 | E-MTAB-17183 | biostudies-arrayexpress
TranscriptomicsGBM-Space: Spatial Transcriptomic Profiling of Glioblastoma (10x Genomics - Visium)
Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single cell and spatial multi-omic a...
ORGANISM(S): Homo sapiens 
2026-09-12 | E-MTAB-17164 | biostudies-arrayexpress
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