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ProteomicsAP-MS of helicase Upf1 in PC12 cells
DNA/RNA helicase Upf1 seems to interact with axonal transcripts in response to nerve growth factor (NGF, A. Ludanyi, M. Gaspari and A. Riccio, unpublished data). In order to shed light on Upf1 mechanism of action and to identify potential associations with molecules having cleavage activity, we perf...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-10 | PXD023586 | Pride
Protein complex Hud Ago2 Impa1 
ProteomicsProteomic analysis of S-nitrosylated nuclear proteins in rat cortical neurons
S-nitrosothiol Resin Assisted Capture(SNORAC) coupled with mass spectrometry analysis has been used to study S-nitrosylated proteins in rat cortical neurons. Proteins were captured on the resin by covalently attaching their former S-NO moiety. Then, nistrosylated proteins were eluted by on-bead dige...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-07-11 | PXD009071 | Pride
Rat S-nitrosylation Cortical neurons Q-exactive 
ProteomicsSecretome analysis of mouse prosate organoids
The objective of the experiment was to compare the secretome of wild type mouse prostate oganoids (WT-mPrOs) to the one obtained from mPrOs bearing a doxycycline inducible ERG expression vector system (ERGM40 mPrOs).
ORGANISM(S): Mus musculus (Mouse) 
2022-03-03 | PXD029660 | Pride
Sbsn Ctla2a Spon2 Spink5 C16orf89 Erg Wnt4 Lcn2 
Proteomics3T3-L1A-derived Extracellular Vesicles Impact the Proteomic Profile of Breast Cancer Cells
In this study, we employed proteomic analysis to gain deeper insights into the role of EVs in breast adiponcosis, providing novel evidence on the role of adipocyte-derived EVs in sustaining mitochondrial metabolism in breast cancer cells.
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD059789 | Pride
Breast cancer Dia Mitochondrial metabolism Orbitrap Fasp Extracellular vescicles 
ProteomicsProteomic analysis of supernatant from NHP heart slices
Proteomic analysis was performed on secreted proteins from non human primate (NHP) heart slices (from Macaca fascicularis) in presence or absence of Cardiac progenitors (CPs) 48 h after radiofrequency ablation (RFA) to mimic tissue damage.
ORGANISM(S): Homo sapiens (Human) Macaca mulatta (Rhesus macaque) 
2022-02-28 | PXD019521 | Pride
Cardiac progenitors Heart Secretome Tissue remodeling 
ProteomicsAdiponectin influences the behavior of stem cells in hormone-resistant breast cancer
Overcoming endocrine-resistance is the major challenge in treating Estrogen receptor (ER)-positive breast cancer. Breast Cancer Stem Cells (BCSCs) are blamed to be the driving force behind poor clinical outcomes and therapeutic resistance. Tumor microenvironment (TME) exerts a selective pressure on ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD059964 | Pride
Breast cancer Endocrine resistance Cancer stem cells : adiponectin Tamoxifen 
ProteomicsProteomic profile of extracellular vesicles released by breast cancer cells
The objective of the experiment was to compare the proteomic profile of extracellular vesicles released by breast cancer cells in basal untreated condition (C1, C2, etc) or treated with the adipokine leptin (L1, L2 etc).
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037266 | Pride
Breast cancer Exosomes 
ProteomicsProteomic analysis of H460 and MCF7 cell lines grown in 2D and 3D culture conditions
In this study we analyzed the proteomic profiles of H460, and MCF7 3D tumor spheroids grown either in standard medium (3D_SM), or in FBSlow conditions (3D_FBSlow) and compared them to their relative 2D cultures (2D). Standard medium consisted of DMEM/F-12 supplemented with 0.5% Glucose, 2.5mM L-Glut...
ORGANISM(S): Homo sapiens (Human) 
2025-01-20 | PXD037256 | Pride
Lung cancer Breast cancer Tumor spheroids Glucose metabolism Metastasis 
ProteomicsTemperature-dependent regulation of the Ochrobactrum anthropi proteome
Ochrobactrum anthropi is a gram-negative rod belonging to the Brucellaceae family, able to colonize a variety of environments, and actually reported as a human opportunistic pathogen. Despite its low virulence, the bacterium causes a growing number of hospital-acquired infections mainly, but not exc...
ORGANISM(S): Ochrobactrum anthropi ATCC 49188 
2016-12-13 | PXD004654 | Pride
Bacteria / heat adaptation / ochrobactrum anthropi / quantitative proteomics / stable isotope dimethyl labeling 
ProteomicsPRM analysis of serum samples obtained from PCa and BPH patients
The aim of this project was the development of a predicitive model combining clinical variables and a panel of proteins measured by targeted-MS able to distinguish PCa from BPH. In particular, a total of 32 formerly N-glycosylated peptides were quantified by PRM.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD035935 | Pride
Proteomics Serum Prm 
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