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UnknownRisk of gastric cancer is associated with PRKAA1 gene polymorphisms in Koreans.
Not available
S-EPMC4093708 | biostudies-literature
UnknownITGA1 polymorphisms and haplotypes are associated with gastric cancer risk in a Korean population.
Not available
S-EPMC3793141 | biostudies-literature
ProteomicsIdentification of ALDH6A1 as a Potential Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome
Various liver diseases, including hepatocellular carcinoma (HCC), have been linked to mitochondrial dysfunction, a condition characterized by abnormal levels of nitric oxide (NO) and reactive oxygen species (ROS). In this study, we subjected the human liver mitochondrial proteome to an extensive qua...
ORGANISM(S): Homo sapiens (Human) 
2020-01-29 | PXD014252 | Pride
Aldh6a1 Nitric oxide Hepatocellular carcinoma Reactive oxygen species Mitochondria 
ProteomicsBAP and ADCK4 interactor proteomic data LC-MS/MS
Although identification of single gene mutations associated with SRNS have yielded insights into pathogenic mechanisms and localized its pathogenesis to glomerular podocytes, the disease mechanisms of SRNS remain obscure. ADCK4 mutations usually manifest as steroid-resistant nephrotic syndrome, and ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD016147 | Pride
Bap Human Adck4 Ip Lc-ms/ms Flag 
ProteomicsIdentifying overtraining biomarkers through proteomic analysis of extracellular vesicles derived from the central nervous system of male mice
Overtraining, which results in central nervous system (CNS)-fatigue-related symptoms, lead to a long-term decline in performance. This study investigated CNS-derived EV protein content under overtraining conditions to identify potential biomarkers. Eight-week-old C57BL/6J mice were randomly divided ...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD069257 | Pride
Biomarker Extracellular vesicle Cns-fatigue Overtraining Proteomic analysis 
ProteomicsADCK4 knockout Human podocyte iTRAQ
Although identification of single gene mutations associated with SRNS have yielded insights into pathogenic mechanisms and localized its pathogenesis to glomerular podocytes, the disease mechanisms of SRNS remain obscure. ADCK4 mutations usually manifest as steroid-resistant nephrotic syndrome, and ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD016725 | Pride
Human Arachidonic acid Adck4 Itraq Podocyte 
TranscriptomicsLinalool, an aromatic terpenoid, rewires transcriptome profile of lipid-loaded HepG2 cells
The microarray results showed that linalool sitimulation of lipid-loaded HepG2 cells rewired the hepatic transcriptome profile, with linalool being comparable to those of fenofibrate. Total of 8,988 genes that were commonly and significantly expressed in all experimental groups, including control he...
ORGANISM(S): Homo sapiens 
2013-04-11 | E-GEOD-45961 | biostudies-arrayexpress
TranscriptomicsHDAC6 functions as a tumor suppressor by activating caspase-independent autophagic cell death in hepatocarcinogenesis
To investigate the specific roles of HDAC6 in the development of liver cancer, we employed large-scale gene expression analysis to identify the molecular signature that may affect enabling characteristics of cancer cells. Differentially expressed genes were analyzed on the Hep3B cells transfected wi...
ORGANISM(S): Homo sapiens 
2012-03-01 | E-GEOD-32068 | biostudies-arrayexpress
TranscriptomicsAberrant Regulation of HDAC2 Mediates Proliferation of Hepatocellular Carcinoma Cells by Deregulating Expression of G1/S Cell Cycle Proteins
To investigate the specific roles of HDAC2 in the development of liver cancer, we employed large-scale gene expression analysis to identify the molecular signature that may affect enabling characteristics of cancer cells. Differentially expressed genes were analyzed on the Hep3B cells transfected wi...
ORGANISM(S): Homo sapiens 
2012-03-01 | E-GEOD-32070 | biostudies-arrayexpress
UnknownCoronary Artery Calcification Score and the Progression of Chronic Kidney Disease.
Not available
S-EPMC9342644 | biostudies-literature
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