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ProteomicsA gephyrin-like protein links cell division and polar elongation in Corynebacteriales
To discover missing players in corynebacterial cell division we used mass-spectrometry based interactomics using formaldehyde as crosslinker, starting with the FtsZ membrane anchor SepF as a bait for co-immunoprecipitation (co-IP) of divisome members. For SepF interactome we carried out the co-IPs u...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2023-07-26 | PXD037255 | Pride
Cell division Corynebacterium glutamicum Interactomics 
ProteomicsIdentification of factors involved in the adaptation to superoxide stress in pathogenic Leptospira
Pathogenic leptospires are responsible for the zoonotic disease leptospirosis. The clinical manifestations of this infection range from a febrile state to a severe life-threatening form characterized by multiple organ hemorrhages. More than one million cases of leptospirosis are currently reported a...
ORGANISM(S): Leptospira interrogans serovar Manilae 
2025-07-10 | PXD055480 | Pride
Leptospira Superoxide Oxidative stress Spirochetes Lc-ms/ms 
ProteomicsEvaluation of the secretome of senescent melanoma cells and the impact of silencing Mfn1 on the senescence-associated secretory phenotype (SASP) by shotgun proteomics analysis.
Cellular senescence is a therapy endpoint in melanoma, and the senescence-associated secretory phenotype (SASP) can affect tumor growth and microenvironment, influencing treatment outcomes. Metabolic interventions can modulate the SASP, and an enhanced mitochondrial energy metabolism supports resist...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD043779 | Pride
Melanoma Cellular senescence Secretome Shotgun proteomics Mitofusins 
ProteomicsLC-MS/MS proteomic analysis of pharyngeal swabs and plasma from MHV-infected and uninfected mice
Recent developments have broadened our perception of SARS-CoV-2, indicating its capability to affect the body systemically beyond its initial recognition as a mere respiratory pathogen. However, the pathways of its widespread are not well-understood. Employing a dual-modality approach, we integrated...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Mus musculus (Mouse) 
2024-12-11 | PXD054355 | Pride
Pharyngeal swabs Mus musculus Mhv Plasma Lc-m/ms 
Proteomics4-HNE modification of human recombinant Dicer
We used mass spectrometry analysis (nanoLC-MS/MS) to map 4-HNE-modified residues of human Dicer exposed in vitro to 4-HNE in a concentration-dependent maner
ORGANISM(S): Homo sapiens (Human) 
2023-11-17 | PXD034113 | Pride
Human dicer 4-hne Lc-ms/ms 
ProteomicsMouse inguinal white adipose tissue (iWAT) LC-MS
Proteomic analysis of whole tissue and isolated mitochondria from iWAT in a mouse model of diet induced obesity with or without SANA.
ORGANISM(S): Mus musculus (Mouse) 
2025-03-24 | PXD030485 | Pride
Iwat Sana 
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
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