Sort   by:  
 Page size 
TranscriptomicsExpression profiling, MDA-MB-231-luc2 response to GW501516
MDA-MB-231-luc2 cells were treated with the PPARd specific agonist GW501516 and the resulting expression changes profiled.
ORGANISM(S): Homo_sapiens 
2013-06-25 | E-MTAB-1262 | biostudies-arrayexpress
TranscriptomicsChIPseq of PPARbeta/delta in MDA-MB-231luc cells
Chromatin-immunoprecipitated with antiPPARD and antiRXR antibodies was performed in MDA-MB-231luc1 cells.
ORGANISM(S): Homo_sapiens 
2013-02-26 | E-MTAB-1097 | biostudies-arrayexpress
UnknownDiffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis.
Not available
S-EPMC4397280 | biostudies-literature
ProteomicsFOXP1 is a transcriptional Coactivator of Wnt/β-catenin signaling in Diffuse Large B-cell Lymphoma
We used a mass spectrometry-coupled lentiviral ‘CD-tagging’ mutagenesis approach to identify genes that activate Wnt/β-catenin signaling. Human A375 melanoma cells containing a β-catenin-driven GFP (green fluorescent protein) transcriptional reporter were transduced with CDBF lentivirus. When integr...
ORGANISM(S): Homo sapiens (Human) 
2016-07-05 | PXD001485 | Pride
Flag apms Gain-of-function screening Wnt signaling Foxp1 
ProteomicsA microRNA/circle RNA axis promotes metastasis through CDR1-mediated anoikis-resistance
Lung cancer is an intrinsically highly metastatic disease and the leading cause of cancer-related deaths worldwide. Although discovery of molecular aberrations in lung adenocarcinomas has led to development of effective targeted therapies, corresponding “drivers” in lung squamous carcinomas (LUSC) h...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD012286 | Pride
Human Cdr1 Lung Cancer Squamous 
ProteomicsNovel KEAP1 activator targeting C151 enhances CUL3 binding and decreases NRF2
Novel KEAP1 activator targeting C151 enhances CUL3 binding and decreases NRF2
ORGANISM(S): Homo sapiens (Human) 
2025-12-10 | PXD056257 | Pride
Nrf2 Keap1 Cul3 
ProteomicsSubstrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase
We inhibited the proteosome to ‘trap’ ubiquitylated substrates on the SCFFBXW11 E3 complex. Comparative mass spectrometry analysis of immunopurified FBXW11 protein complexes before and after proteosome inhibition revealed known and putatively novel substrates.
ORGANISM(S): Homo sapiens (Human) 
2014-10-24 | PXD001062 | Pride
Btrc Fbxw11 E3 ubiquitin ligase 
UnknownDifferential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes.
Not available
S-EPMC7343213 | biostudies-literature
ProteomicsIdentification and Characterization of MCM3 as a KEAP1 Substrate
KEAP1 is a substrate adaptor protein for a CUL3-based E3 ubiquitin ligase. Ubiquitylation and degradation of the antioxidant transcription factor NRF2 is considered the primary function of KEAP1; however, few other KEAP1 substrates have been identified. Because KEAP1 is altered in a number of human ...
ORGANISM(S): Homo sapiens (Human) 
2017-10-12 | PXD003929 | Pride
Hek293t Di-gly Apms Silac Label free quantification 
UnknownB cell engagement with HIV-1 founder virus envelope predicts development of broadly neutralizing antibodies.
Not available
S-EPMC8245051 | biostudies-literature
Sort   by:  
 Page size