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ProteomicsProteome Dynamics of the Cotyledonary Haustorium and Endosperm in the Course of Germination of Euterpe oleracea Seeds
The role of the cotyledonary haustorium (CH) in the mobilization of nutrient reserves in the endosperm of species of the palm family Arecaceae is a moot question. To shed light on this matter, we present here an analysis of the quantitative proteome changes associated with four developmental stages ...
ORGANISM(S): Euterpe oleracea 
2021-01-27 | PXD017481 | Pride
Cotyledonary haustorium Thermo q exactive Euterpe oleracea Endosperm Nanoesi ltq-orbitrap velos 
ProteomicsMouse stool samples in response to antibiotic treatment
Background and Objectives: Antibiotic (ABx) therapy is associated with an increased risk for Crohn´s Disease but the underlying mechanisms are unknown. We observed high fecal serine protease activity (PA) to be a frequent side effect of ABx therapy in patients. The aim of the present study was to un...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-11 | PXD007914 | Pride
Mouse Antibiotic treatment Velos Intestinal barrier Stool Protease activity 
ProteomicsON THE ACCURACY, PRECISION AND STATISTICAL SIGNIFICANCE OF COMPRESSED RATIOS IN ISOBARIC LABELLING
Despite the outstanding advantages that isobaric labelling has to offer in quantitative proteomics, its precision and accuracy are undermined by ratio compression, which is consequence of the co-isolation of peptides within a selected isolation window. Here, using the two-proteomes approach we inves...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2016-08-08 | PXD003640 | Pride
Isobaric labelling Statistics Accuracy Ratio compression Precision 
ProteomicsMouse PPAR gamma with/without 15-keto-PGE2
15-keto-PGE2 is proposed as an endogenous ligand of PPAR gamma. The modification of 15-keto-PGE2 can induce PPAR gamma transcriptional activation. This project aims to identify the binding site of 15-keto-PGE2 on PPAR gamma.
ORGANISM(S): Mus musculus (Mouse) 
2025-02-17 | PXD059654 | Pride
15-keto-pge2 Ppar gamma 
ProteomicsIdentification of Poly Ethylene Glycol (PEG) and PEG-based Detergents Using Peptide Search Engines
Polyethylene glycol (PEG) is one of the most common polymer contaminations in MS samples. At present, the detection of PEG and other polymers relies largely on manual inspection of raw data which is laborious and frequently difficult due to sample complexity and retention characteristics of polymer ...
ORGANISM(S): Rattus rattus (Black rat) 
2018-05-28 | PXD009376 | Pride
Automated Polymer Mass spectrometry Peptide search engine Peg Poly ethylene glycol 
ProteomicsIdentification of ubiquitin binding protein using TurboID analysis
Purines serve as the building blocks for DNA and RNA, confer cellular energy and signaling. Purines are generated by de novo synthesis pathway and salvage pathway. Under purine-depleted or other cellular stresses, enzymes in the purine de novo synthesis pathway form a dynamic and reversible condensa...
ORGANISM(S): Homo sapiens (Human) 
2023-10-06 | PXD027946 | Pride
Asb11 paics ubp 
ProteomicsComparative proteomic analysis of different parts of Taenia hydatigena
Taenia hydatigena, a globally distributed parasite, is a canine tapeworm and causes huge economic losses in the food industry. Using LC-MS/MS, the proteomes of T. hydatigena cyst scolex, designated as CS, and the cyst without the scolex, designated as CWS, were profiled and a total of 764 different ...
ORGANISM(S): Taenia hydatigena (Tapeworm) 
2021-04-22 | PXD023543 | Pride
Cyst Taenia hydatigena Scolex 
ProteomicsThe RNA Polymerase II factor RPAP1 is critical for Mediator-driven transcription and cell identity
The RNA Polymerase II Associated Protein 1 (RPAP1) is conserved across metazoa and critical for stem cell differentiation in plants, however, very little is known about its mechanism of action or its role in mammalian cells. Here, we report that RPAP1 is essential for the expression of lineage spec...
ORGANISM(S): Mus musculus (Mouse) 
2018-01-10 | PXD007114 | Pride
Cell identity Rna pol ii Rpap1 Mediator 
ProteomicsAge effects in the extracellular matrix (ECM) proteome of the mouse left ventricle
Matrix metalloproteinases (MMPs) collectively degrade all extracellular matrix (ECM) proteins. MMP-9 has the strongest link to development of cardiac dysfunction. Aging is associated with increased MMP-9 expression in the left ventricle (LV) and reduced cardiac function. We investigated the effect o...
ORGANISM(S): Mus musculus (Mouse) 
2018-07-05 | PXD002488 | Pride
Ecm proteome Mouse Left ventricle Aging hplc-esi-ms/ms 
ProteomicsASB11 controls purinosome formation through PAICS ubiquitination
Purine act as building block for DNA and RNA, provide cellular energy and signaling, and can generate cofactors such as NADH and coenzyme A. Purine de novo synthesis pathway begins with amino acids, ribose 5-phosphate, CO2 and NH3 with 6 enzymes and 10 enzymatic steps to convert PRPP to IMP. In prev...
ORGANISM(S): Homo sapiens (Human) 
2023-10-06 | PXD025298 | Pride
Purine de novo synthesis Asb11 Paics Purinosome 
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