Sort   by:  
 Page size 
UnknownPeptiCHIP: A Microfluidic Platform for Tumor Antigen Landscape Identification.
Not available
S-EPMC8552492 | biostudies-literature
ProteomicsExploiting trogocytosis by Immunopeptidomics to profile tumor associated antigens (TAA) actively targeted by tumor specific T cells in leukemia.
We employed PeptiCHIP Immunopeptidomics to profile tumor associated antigens (TAA) actively targeted by tumor specific T cells by exploiting the trogocytosis effect, whereby antigen presenting cells (APCs) nibble portions of the cognate T cell containing the TCR. The antigen presenting cells were th...
ORGANISM(S): Homo sapiens (Human) 
2023-09-07 | PXD035344 | Pride
T cell Leukemia Peptichip Trogocytosis Taa Ligandomics Tcr Hla-i Human Mhc-i Immunopeptidomics 
ProteomicsImmunopeptidome of Renal Cell Carcinoma (RCC) and Bladder Cancer (BC) Patient-Derived Tumor Organoids (PDTOs)
Patient-Derived Tumor Organoids (PDTOs) have emerged as physiologically relevant systems, retaining genomic and phenotypic features of patient tumors and enabling drug response prediction. Here, we established a patient-specific pipeline to evaluate precision immunotherapy in Renal Cell Carcinoma (R...
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD068567 | Pride
Ligandome Pdtos Mhc Hla-i Dda Immunopeptidomics Hla Immunopeptidome Ligandomics Patient-derived tumor organoids Renal cell carcinoma Rcc Timstof scp Mhc-i Bladder cancer 
ProteomicsImmunopeptidomics of Acute Myeloid Leukemia (AML) Blast cells after Therapy-Induced Senescence (TIS) with Cytarabine.
Resistance or relapse upon chemotherapy are major determinants of treatment failure in acute myeloid leukemia (AML). Therapy-induced senescence (TIS) is a potential outcome of chemotherapy, but its immunological consequences in AML remain unclear. We show that ex-vivo chemotherapy induces senescence...
ORGANISM(S): Homo sapiens (Human) 
2026-08-13 | PXD068731 | Pride
Immunopeptidomics Therapy-induced senescence Tis Hla Ligandome Mhc Cytarabine Ligandomics Immunopeptidome Timstof scp Acute myeloid leukemia Aml 
ProteomicsImmunopeptidomics by use of a microfluidics chip.
A microfluidics technology was implemented to the immunoaffinity purification process of MHC peptides in Ligandomics/Immunopeptidomics. The thus purified HLA peptides were analysed by LCMS with the nanoElute LC and TimsTOF Pro Mass Spectrometer from Bruker. The aim of the microfluidics implementatio...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD022194 | Pride
Human Bladder cancer Ligandome Patient derived organoid Hla-i Renal cell carcinoma Microfluidics Ovarian cancer Immunopeptidome Jy cell line Chip Mhc-i Rcc 
Sort   by:  
 Page size