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TranscriptomicsRho directs widespread termination of intragenic and stable RNA transcription
The transcription termination factor Rho is a global regulator of RNA polymerase (RNAP). Although individual Rho-dependent terminators have been studied extensively, less is known about the sites of RNAP regulation by Rho on a genome-wide scale. Using chromatin immunoprecipitation and microarrays (...
ORGANISM(S): Escherichia coli 
2010-05-18 | E-GEOD-16562 | biostudies-arrayexpress
TranscriptomicsRegulator trafficking on bacterial transcription units in vivo
The in vivo trafficking patterns on DNA by the bacterial regulators of transcript elongation Sigma70, Rho, NusA, and NusG and the explanation for high promoter-proximal levels or peaks of RNA polymerase (RNAP) are unknown. Genome-wide ChIP-chip on E. coli revealed distinct association patterns of r...
ORGANISM(S): Escherichia coli 
2010-05-14 | E-GEOD-13938 | biostudies-arrayexpress
ProteomicsThe cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism
Cohesin structures the genome through the formation of chromatin loops and by holding together the sister chromatids. The acetylation of cohesin’s SMC3 subunit is a dynamic process that involves the acetyltransferase ESCO1 and deacetylase HDAC8. Here we show that this cohesin acetylation cycle contr...
ORGANISM(S): Homo sapiens (Human) 
2022-03-14 | PXD032185 | Pride
Cohesin acetylation cycle Ctcf Esco1 Pds5a Cohesin Hdac8 3d genome Wapl Chromatin loops Pds5b 
ProteomicsCondensin II Activation by the centromeric protein M18BP1
Condensin I and condensin II promote drastic spatial compaction (condensation) of the genome upon mitotic entry. Condensin I binds chromatin only after dissolution of the nuclear envelope in prophase. Conversely, condensin II is nuclear throughout the cell cycle and initiates chromosome condensation...
ORGANISM(S): Homo sapiens (Human) 
2025-07-09 | PXD051886 | Pride
Sda Sulfo-sda Condensin Cryo-em Xl-ms M18bp1 Crosslinking 
ProteomicsArabidopsis chloroplast N-terminome
Protein N-termini are prone to post translational modification and are major determinants of protein stability in bacteria, eukaryotes, and perhaps also in chloroplasts. Most chloroplast proteins undergo N-terminal maturation, but this is poorly understood due to insufficient experimental informatio...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2017-11-14 | MSV000081716 | MassIVE
UnknownCommon variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.
Not available
S-EPMC4154629 | biostudies-literature
UnknownExtension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.
Not available
S-EPMC2518503 | biostudies-literature
UnknownAssociation of BMI and Cognitive Performance in the Diabetes Prevention Program Outcomes Study.
Not available
S-EPMC12636062 | biostudies-literature
Unknown3D genomics across the tree of life reveals condensin II as a determinant of architecture type.
Not available
S-EPMC8172041 | biostudies-literature
UnknownGenetic determinants of micronucleus formation in vivo.
Not available
S-EPMC10917660 | biostudies-literature
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