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MetabolomicsA multi-omics approach reveals functions of Secretory Carrier-Associated Membrane Proteins in wood formation of Populus trees
Secretory Carrier-Associated Membrane Proteins (SCAMPs) are highly conserved proteins that are involved in membrane trafficking. An integrated approach was taken to elucidate function of SCAMPs in wood formation of Populus trees. The metabolomics analyses were performed in woody tissues of transgeni...
2018-01-08 | MTBLS478 | MetaboLights
ProteomicsUnderstanding early AutoAb signatures in Pituitary Adenomas using CDI HuProt™ (Human Proteome Microarray)
CDI HuProt™ (Human Proteome Microarray), was used to study Pituitary Adenomas PAs (Acromegaly, Cushing's and NFPA) using serum samples, from around 14 individuals (4 Healthy control, 4 Acromegaly, 3 Cushing’s and 3 NFPAs patient samples) were used study their autoantibody profiles. Patient serum sam...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-11947 | biostudies-arrayexpress
ProteomicsExcretory-secretory proteome of nematode Heligmosomoides polygyrus developed in colitic conditions
The aim of the study was to evaluate excretory-secretory protein set produced by nematode H. polygyrus L4 stage male and female developed in colitic milienu. Mass spectrometry was used to identify proteins. OmicsBox was used to investigate the functions of the discovered proteins.
ORGANISM(S): Heligmosomoides polygyrus bakeri 
2023-10-24 | PXD041516 | Pride
Lc-ms/ms Nematode Heligmosomoides polygyrus bakeri Excretory-secretory products Colitis 
ProteomicsIn-depth proteome analysis of FFPE mammary secretory carcinoma specimens
Mammary secretory carcinoma (MSC) is one of the rarest types of breast cancer accounting for less than 0.15% of all breast cancers. Traditionally, MSC is considered that it belongs to the phenotypic spectrum of basal-like triple-negative breast carcinoma (BL-TNBC). Here, we present a study of MSC fo...
ORGANISM(S): Homo sapiens (Human) 
2018-02-27 | PXD005303 | Pride
Tmt Ffpe Quantitative proteomics Secretory carcinoma 
ProteomicsProteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane
In the present work neutrophil subcellular fractionation by density gradient centrifugation was conducted in order to perform a quantitative proteomic profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane
ORGANISM(S): Homo sapiens (Human) 
2017-06-23 | PXD005559 | Pride
Lc-msms Quantitative proteomic profiling Secretory vesicles Human neutrophil granules 
ProteomicsMouse osteoclast secretory lysosomes nLC-ESI-MS/MS
To survey the proteome of osteoclast secretory lysosomes, we used superparamagnetic iron oxide nanoparticles (SPIONs) to enrich for these endo-lysosomal-related organelles from murine osteoclast cultures. Briefly, large scale murine bone marrow monocyte (BMM)-derived osteoclast cultures were ‘pulsed...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-25 | PXD037006 | Pride
Lysosome Lro Mouse Spion Osteoclast Secretory lysosome 
ProteomicsProteomic analysis of secretory granules in dopaminergic neurons of Parkinson`s disease
Parkinson disease (PD) is the second most common age-related neurodegenerative disorder, which is related to neurotransmitter secretion impartment and the dysfunction of vesicle transport. Secretory granules (SGs) are a class of intracellular vesicles different from synaptic vesicles (SVs) in neuron...
ORGANISM(S): Homo sapiens (Human) 
2021-08-26 | PXD023937 | Pride
Parkinson`s disease Vesicle transport Secretory granule 
ProteomicsMouse osteoclast secretory lysosomes nLC-ESI-MS/MS - WT vs Slc37a2 KO
To survey the proteome of osteoclast secretory lysosomes, we used superparamagnetic iron oxide nanoparticles (SPIONs) to enrich for these endo-lysosomal-related organelles from murine osteoclast cultures. Briefly, large scale murine bone marrow monocyte (BMM)-derived osteoclast cultures were ‘pulsed...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-25 | PXD037813 | Pride
Lysosome Lro Mouse Spion Osteoclast Secretory lysosome 
UnknownEffector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells.
Not available
S-EPMC3034720 | biostudies-literature
TranscriptomicsTowards a reference human platelet transcriptome: evaluation of inter-individual correlations and of its relationship with a platelet proteome
For the anucleate platelet it has been unclear how well platelet transcriptomes correlate among different donors or across different RNA profiling platforms, and what the transcriptomes’ relationship is with the platelet proteome. We generated RNA-seq pro-files of the long R...
ORGANISM(S): Homo sapiens 
2015-01-20 | E-GEOD-50858 | biostudies-arrayexpress
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