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MetabolomicsImpact of myocardial reperfusion on human plasma lipidome
The primary aim of the study is to investigate the temporal changes in plasma lipidome before and after reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) and their association with myocardial injury. We found that 56% of the identified lipid species were significantly a...
2022-02-07 | MTBLS3839 | MetaboLights
GenomicsMMSET Induces Global and Focal Changes in Histone Methylation in Myeloma Cells
We investigated genome wide distribution of H3K36me2, H3K36me3 and H3K27me3 in the presence and absence of MMSET protein. MMSET overexpression in t(4;14)+ myeloma leads to global loss redistribution of H3K36me2 and genome-wide loss of H3K27 methylation. Despite the gloal decrease in H3K27me3, speci...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-57977 | biostudies-arrayexpress
UnknownSquama Manitis Extract Exhibits Broad-Spectrum Antibacterial Activity Through Energy and DNA Disruption Mechanisms.
Not available
S-EPMC12383583 | biostudies-literature
UnknownIntestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Not available
S-EPMC6368617 | biostudies-literature
TranscriptomicsTreatment of multiple myeloma cells with EZH2 small molecule inhibitor
We investigated differential gene expression in response to treatment of multiple myeloma cells with EZH2 inhibitor RNA-seq in two cell lines
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-57478 | biostudies-arrayexpress
GenomicsMMSET alters EZH2 Binding in Myeloma Cells
We investigated EZH2 binding in the presence and absence of MMSET protein. MMSET overexpression in t(4;14)+ myeloma leads to global loss of H3K27 methylation and redistribution of EZH2 binding throughout the genome ChIP-seq for EZH2 in two cell types
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-57632 | biostudies-arrayexpress
UnknownImprovements in health-related quality of life in patients with transfusion-dependent β-thalassemia after exagamglogene autotemcel.
Not available
S-EPMC12757516 | biostudies-literature
ProteomicsCharacterization of Primary Patient B-cells under Various Stimulation Conditions
The goal of this project was to compare the effects of differential stimulation of primary patient B-cells with CD40L, CpG, anti-IgM, and IL4 individually and in combination. Additionally, we observed a phenomenon where anti-IgM+CpG treatment resulted in a lymphoma-like phenotype and sought to compa...
ORGANISM(S): Homo sapiens (Human) 
2025-08-21 | PXD016961 | Pride
Human Igm B-cells Ms3 Tmt Immunology Cd40l Hbl-1 Sps-ms3 Cpg Il4 11-plex 
UnknownHistone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.
Not available
S-EPMC4154646 | biostudies-literature
UnknownDeterminants of COVID-19 Vaccine Engagement in Algeria: A Population-Based Study With Systematic Review of Studies From Arab Countries of the MENA Region.
Not available
S-EPMC9196869 | biostudies-literature
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