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ProteomicsA chemical strategy for protease substrate profiling
Here, we introduce a simple method, termed CHOPS, for the discovery of protease substrates. CHOPS exploits a 2-pyridinecarboxaldehyde (2PCA)-biotin probe, which selectively biotinylates protein N-termini except those with proline in the second position. CHOPS can, in theory, discover substrates for...
ORGANISM(S): Homo sapiens (Human) 
2019-04-23 | PXD013019 | Pride
Chops Silac N-terminomics 
ProteomicsGlobal proteomics of HEK293T cells treated with Val-boroPro for 48h
Global proteomics of HEK293T cells treated with Val-boroPro for 48h
ORGANISM(S): Homo sapiens (Human) 
2020-10-14 | PXD015978 | Pride
Val-boropro Tmtsixplex 
UnknownPsychedelic-Assisted Therapy: Emerging Treatments in Mental Health Disorders
Not available
S-EPMC8574982 | biostudies-literature
ProteomicsTarget identification of CQ31, a selective activator of the CARD8 inflammasome
Target identification of CQ31 using the photoreactive diazirine-alkyne probe, CQ73.
ORGANISM(S): Homo sapiens (Human) 
2021-11-17 | PXD027707 | Pride
Pepd Xpnpep1 Cq31 Inflammasome Tmt-sixplex 
UnknownHeat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial.
Not available
S-EPMC3895386 | biostudies-literature
UnknownA wearable aptamer nanobiosensor for non-invasive female hormone monitoring.
Not available
S-EPMC10954395 | biostudies-literature
UnknownMulticenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas.
Not available
S-EPMC5993168 | biostudies-literature
UnknownBrentuximab vedotin in the front-line treatment of patients with CD30+ peripheral T-cell lymphomas: results of a phase I study.
Not available
S-EPMC4171358 | biostudies-literature
ProteomicsDPP9 activity and not protein binding inhibits the CARD8 inflammasome
Inflammasomes are multiprotein complexes formed in response to pathogens. NLRP1 and CARD8 are related proteins that form inflammasomes, but the pathogen-associated signal(s) and the molecular mechanisms controlling their activation have not been established. Inhibitors of the serine dipeptidyl pept...
ORGANISM(S): Homo sapiens (Human) 
2019-10-23 | PXD015047 | Pride
Val-boropro Card8 Dpp9 
UnknownProstate-Specific Antigen Failure and Risk of Death Within Comorbidity Subgroups Among Men With Unfavorable-Risk Prostate Cancer Treated in a Randomized Trial.
Not available
S-EPMC5791839 | biostudies-literature
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