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ProteomicsTurboID-mediated proximity labeling of DAF-16/FOXO in wild-type and daf-2(e1370) mutants in C. elegans
TurboID-mediated proximity labeling of the aging and stress regulatory transcription factor DAF-16/FOXO in wild-type and daf-2(e1370) mutants in C. elegans. Endogenous DAF-16 was C-terminally tagged with the biotin ligase TurboID using CRISPR/Cas9- genome editing. In vivo proximity labeling of the ...
ORGANISM(S): Caenorhabditis elegans 
2025-12-29 | PXD053591 | Pride
Foxo Turboid Insulin / igf signaling Daf-16 Caenorhabditis elegans Proximity labeling 
ProteomicsTurboID-mediated proximity labeling for screening interacting proteins of FIP37 in Arabidopsis
Proximity labeling (PL) was recently developed to detect protein–protein interactions (PPIs) and members of subcellular multiprotein structures in living cells. Proximity labeling is conducted by fusing an engineered enzyme with catalytic activity, such as biotin ligase, to a protein of interest (ba...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-01-26 | PXD043041 | Pride
Proximity labeling (pl)  turboid  protein–protein interactions (ppis)  biotin  m6a  fip37 
ProteomicsAn improved TurboID-based proximity labeling pipeline in C. elegans by biochemical depletion of endogenously biotinylated carboxylases
To review an improved proximity-labeling strategy that uses the improved E. coli biotin ligase TurboID to characterize C. elegans protein complexes, the interactome of a presynaptic active zone protein, ELKS-1, was analyzed as proof of principle. A significant constraint on the sensitivity of TurboI...
ORGANISM(S): Caenorhabditis elegans 
2022-09-12 | PXD034639 | Pride
Synapse Imac Apex2 Proximity-dependent protein labeling Hrp Biotinylated carboxylase depletion Turboid Caenorhabditis elegans 
UnknownTurboID-based proximity labeling reveals that UBR7 is a regulator of N NLR immune receptor-mediated immunity.
Not available
S-EPMC6642208 | biostudies-literature
UnknownTurboID-mediated proximity labeling for screening interacting proteins of FIP37 in Arabidopsis.
Not available
S-EPMC10727772 | biostudies-literature
ProteomicsApplication of TurboID-mediated proximity labeling and phosphoproteomics for mapping a GSK3 kinase signaling network in Arabidopsis
Transient protein-protein interactions (PPIs), such as those between posttranslational modifying enzymes and their substrates, play key roles in cellular regulation, but are difficult to identify. Here we demonstrate the application of enzyme-catalyzed proximity labeling (PL), using the engineered p...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-05-10 | PXD017085 | Pride
Proximity labeling Turboid Mass spectrometry Protein interactome Protein-protein interaction Gsk3 kinase Phosphoproteomics Plant Biotinylation 
Proteomicsphotoactivation-dependent proximity labeling (PDPL) MS
we report a photoactivation-dependent proximity labeling (PDPL) method designed by genetically attaching photosensitizer protein miniSOG to a protein of interest (POI). Triggered by blue light, singlet oxygen is generated, enabling temporally-resolved chemical probe labeling.
ORGANISM(S): Homo Sapiens 
2022-06-22 | PXD034811 |
UnknownDepletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans.
Not available
S-EPMC9437848 | biostudies-literature
ProteomicsExploring the interactome of Miro2 in hippocampal neural stem cells through TurboID-mediated proximity labeling
Mitochondrial Rho-GTPase (Miro), a protein found on the outer mitochondrial membrane, is required for mitochondrial transport, mitochondrial dynamics, and mitochondrial Ca2+ homeostasis. We previously reported that Miro2 plays a role in the survival of hippocampal neural stem (HCN) cells, with effec...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-02-23 | PXD055479 | Pride
Proximity labeling Turboid Rattus norvegicus Rhot2 Lc/ms-ms Hippocampal neural stem cell 
UnknownIdentification of the Bok Interactome Using Proximity Labeling.
Not available
S-EPMC8201613 | biostudies-literature
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