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ProteomicsRelating human gut metagenome and metaproteome
Gut microbiome research is rapidly moving towards the functional characterization of the microbiota by means of shotgun meta-omics. Here, we selected a cohort of healthy subjects from an indigenous and monitored Sardinian population to analyze their gut microbiota using both shotgun metagenomics and...
ORGANISM(S): human gut metagenome 
2017-07-19 | PXD005780 | Pride
Gut metagenome Gut metaproteome Metaproteomics 
ProteomicsBenchmarking low- and high-throughput protein cleanup and digestion methods for human fecal metaproteomics
Benchmarking low- and high-throughput protein cleanup and digestion methods for human fecal metaproteomics
ORGANISM(S): Homo sapiens (Human) human gut metagenome 
2024-05-31 | PXD049294 | Pride
Metaproteome Mass spectrometry Fasp Gut microbiota Sample preparation Multiwell plate 
ProteomicsMetaproteomic assessment of gut microbial and host functional perturbations in Helicobacter pylori-infected patients subjected to an antimicrobial protocol
The impact of therapeutic interventions on the human gut microbiota (GM) is a clinical issue of paramount interest given the strong interconnection between microbial dynamics and human health. Orally administered antibiotics are known to reduce GM biomass and modify GM taxonomic profile. However, th...
ORGANISM(S): Homo sapiens (Human) human gut metagenome 
2023-12-14 | PXD042946 | Pride
Antibiotics Metaproteomics Helicobacter Mass spectrometry Gut microbiota Human microbiome 
ProteomicsMulti-omic biogeography of the gastrointestinal microbiota of a pre-weaned lamb
Here, we used reverse-phase liquid chromatography-coupled tandem mass spectrometry to study the pre-weaned lamb proteome and metaproteome in ten different gastrointestinal tracts: rumen, reticulum, omasum, abomasum, duodenum, jejunum, ileum, cecum, colon, and rectum.
ORGANISM(S): Microbiota Ovis aries 
2017-12-14 | PXD008192 | Pride
Ruminant Metaproteomics Mucosa Microbial community Sheep 
ProteomicsMetaproteomic portrait of the healthy human gut microbiota
Metaproteomic portrait of the healthy human gut microbiota. Re-analysis of existing datasets, selected based on the following inclusion criteria: human cohort including at least 5 healthy (clearly not labeled as diseased) adult (>18 years old) individuals; data derived from LC-MS/MS DDA label-free a...
ORGANISM(S): human gut metagenome 
2024-05-16 | PXD046818 | Pride
Metaproteomics Healthy human gut Functions Gut microbiota Stool 
ProteomicsSheep fecal microbiota - Diversity and functions of the sheep faecal microbiota: a multi-omic characterization
Characterization of the fecal metaproteome of dairy sheep
ORGANISM(S): Microbiota 
2017-02-22 | PXD004524 | Pride
Metaproteomics Sheep Stool 
ProteomicsThe sheep host fecal proteome - The Sarda Sheep Host Fecal Proteome
Characterization of the fecal (host) proteome in 5 Sarda sheep
ORGANISM(S): Ovis aries 
2018-01-15 | PXD006145 | Pride
Proteomics Gut Stool Sheep 
ProteomicsFecal metaproteome profiles of celiac disease patients with poly-autoimmunity
Twenty-eight subjects were selected for the study from among celiac disease patients regularly followed at the Medical Clinic of the University of Sassari. Celiac disease (CD) was diagnosed according to international guidelines. Patients were divided into two groups of 14 subjects based on the prese...
ORGANISM(S): Homo sapiens (Human) human gut metagenome 
2025-10-16 | PXD069517 | Pride
Gut microbiome Celiac disease Autoimmunity Metaproteomics 
ProteomicsColon cancer luminal contents metaproteomics
Metaproteomics of surgically collected luminal contents from colon cancer patients
ORGANISM(S): Homo sapiens (Human) gut metagenome 
2022-05-19 | PXD017467 | Pride
Colon cancer Human Gut Microbiota Metaproteomics 
ProteomicsMouse_T1D_microbiota - Clostridial Butyrate Biosynthesis Enzymes Are Significantly Depleted in the Gut Microbiota of Nonobese Diabetic Mice
A metaproteomic approach was exploited to investigate microbiota protein expression in feces from Eα16 and NOD mice at 10 weeks of age (n=6 vs 6 mice)
ORGANISM(S): Mus musculus (Mouse) gut metagenome 
2018-10-15 | PXD003616 | Pride
Butyrate Gut microbiota Mouse Diabetes Metaproteomics 
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