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UnknowniTRAQ-Based Proteomics Analysis of Plasma of Myasthenia Gravis Patients Treated with Jia Wei Bu Zhong Yi Qi Decoction.
Not available
S-EPMC6930785 | biostudies-literature
UnknownApproaches and outcomes of adalimumab discontinuation in patients with well-controlled inflammatory arthritis: a systematic search and review.
Not available
S-EPMC11684048 | biostudies-literature
UnknownSustained hippocampal neuroinflammation and subsequent glutamatergic dysfunction in juvenile idiopathic arthritis: evidence from proton magnetic resonance spectroscopy (<sup>1</sup>H-MRS).
Not available
S-EPMC12754929 | biostudies-literature
MetabolomicsFatty acid oxidation protects cancer cells from apoptosis through increasing mitochondrial membrane lipids

Overcoming resistance to chemotherapies remains a major unmet need for cancers such as triple negative breast cancer (TNBC). Therefore, mechanistic studies to provide insight for drug development are urgently needed to overcome TNBC therapy resistance. Recently, an important role of fatty acid β-...

2022-05-31 | MTBLS4709 | MetaboLights
ProteomicsUSP36 stabilizes nucleolar Snail1 to promote ribosome biogenesis and cancer cell survival upon ribotoxic stress
Tumor growth requires elevated ribosome biogenesis. Targeting ribosomes is an important strategy for cancer therapy. The ribosome inhibitor, homoharringtonine (HHT), is used for the clinical treatment of leukemia, yet it is ineffective for the treatment of solid tumors, the reasons for which remain ...
ORGANISM(S): Homo sapiens (Human) 
2023-09-26 | PXD045622 | Pride
Usp36  snail1  ribosome biogenesis  ribotoxic stress 
ProteomicsGlobal and phospho-proteome of Hek293T treated with kinase inhibitors
We examine the changes in HEK293T overexpressing alpha-synucleinA53T-GFP when treated with kinase inhibitors (SB203580, GF109203X,SB202190, Enzastaurin, VX-745). Main findings is altered protein translation, with an increase in lysosomal proteins for all compounds save VX-745
ORGANISM(S): Homo sapiens (Human) 
2021-07-05 | PXD024508 | Pride
Lc-msms Enzastaurin Hek293t Alpha-synuclein Gf109203x Sb202190 Vx-745 Sb203580 
GenomicsEvolutionary Significance of DNA Methylation in Human and Chimpanzee Brains
We compared the genome-wide patterns of DNA methylation in the brains of humans to those of our closest evolutionary relative, chimpanzees, using base-pair resolution whole-genome methylation maps of the prefrontal cortex. Our data reveal that the prefrontal cortex is the most heavily methylated am...
ORGANISM(S): Human 
2012-09-04 | E-GEOD-37202 | biostudies-arrayexpress
UnknownA prospective international multisite randomized controlled trial of water exchange with and without distal cap(s) in adenoma detection.
Not available
S-EPMC12850690 | biostudies-literature
UnknownMetabolomics analysis of the potential mechanism of Yi-Guan-Jian decoction to reverse bone loss in glucocorticoid-induced osteoporosis.
Not available
S-EPMC10242983 | biostudies-literature
ProteomicsLabel-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line
Hepatitis B virus (HBV) infection is a major health problem worldwide. Recent evidence suggests that various viruses can manipulate the infection process by secretion of specific viral and cellular components into exosomes, small nanometer-sized (30-150 nm) vesicles secreted from various cells. Howe...
ORGANISM(S): Homo sapiens (Human) 
2017-03-01 | PXD004724 | Pride
Hbv  exosomes  hepatocyte  proteasome  label-free quantification 
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