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ProteomicsDynamic of the Grb2 interactome in primary cells by DDA-MS
We applied AP-MS to quantify Grb2 interaction dynamics in primary T cells. Data generated here in shotgun/DDA mode were used to build a high quality Grb2 binders-specific SWATH assay library for high-throughput targeted analysis of DIA data.
ORGANISM(S): Mus musculus (Mouse) 
2017-03-09 | PXD003973 | Pride
Primary t cells Ms Grb2 Interactome Dda 
ProteomicsA tissue-based draft map of the murine MHC class I immunopeptidome
The array of peptides presented to CD8+ T cells by major histocompatibility complex (MHC) class I molecules is referred to as the MHC class I immunopeptidome. Although the MHC class I immunopeptidome is ubiquitous in mammals and represents a critical component of the adaptive immune system, very lit...
ORGANISM(S): Mus musculus (Mouse) 
2018-06-19 | PXD008733 | Pride
Tissue Mass spectrometry Mhc Immunopeptidome Map 
ProteomicsEpigenetics and Proteomics join Transcriptomics on the quest towards TB Biomarkers
Even though recent reports estimate a reduction in the spread and contraction of Tuberculosis (TB), 30 % of the world population are currently being latently infected by Mycobacterium tuberculosis (Mtb). This latent infection can at any time develop into active disease. Biomarkers to monitor this pr...
ORGANISM(S): Homo sapiens (Human) 
2015-08-26 | PXD001960 | Pride
Proteomics Tuberculosis Epigenetics Transcriptomics Biomarkers 
ProteomicsDynamic of the Grb2 interactome in primary cells by DIA-MS
We applied AP-SWATH to quantify Grb2 interaction dynamics in primary T cells with a high level of reproducibility and accuracy. We concluded that AP-SWATH is a robust approach to quantify signaling dynamics in primary cells and could be further expanded to additional hub proteins using a range of ce...
ORGANISM(S): Mus musculus (Mouse) 
2017-03-09 | PXD003972 | Pride
Swath Dia-ms Primary t cells Grb2 Interactome 
ProteomicsDigital mapping of immunopeptidomes: SWATH-MS
We present a novel mass spectrometry-based high-throughput workflow and an open-source computational and data resource to reproducibly identify and quantify HLA-associated peptides. Collectively, the resources support the generation of HLA allele-specific peptide assay libraries consisting of consen...
ORGANISM(S): Homo sapiens (Human) 
2015-07-14 | PXD001904 | Pride
Dia Swath-ms Hla Immunopeptidome 
ProteomicsDigital mapping of immunopeptidomes
We present a novel mass spectrometry-based high-throughput workflow and an open-source computational and data resource to reproducibly identify and quantify HLA-associated peptides. Collectively, the resources support the generation of HLA allele-specific peptide assay libraries consisting of consen...
ORGANISM(S): Homo sapiens (Human) 
2015-07-14 | PXD001872 | Pride
Dia Swath-ms Hla Immunopeptidome 
ModelsCaron2010_mTORsignalingNetwork_ActivityFlow
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model ha...
2005-01-01 | MODEL1012220004 | BioModels
ModelsCaron2010_mTOR_SignalingNetwork
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model ha...
2005-01-01 | MODEL1012220002 | BioModels
ModelsCaron2010_mTORC1_UpstreamRegulators
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model ha...
2005-01-01 | MODEL1012220003 | BioModels
ProteomicsIsolation of mouse and human MHC class I- and II-associated peptides for the analysis of immunopeptidomes by mass spectrometry
Immunopeptidomics is an emerging field that fuels and guides the development of vaccines and immunotherapies. More specifically, it refers to the science of investigating the composition of peptides presented by major histocompatibility complex (MHC) class I and class II molecules using mass spectro...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-12-07 | PXD028633 | Pride
Mhc class i associated peptides Mass spectrometry Human Immunopeptidome Mhc class ii associated peptides Mouse 
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