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ProteomicsRat DRG CIPN versus Vehicle-treatment_DIA-MS
Chemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect of cancer treatment, often leading to cessation of therapy due to lack of adequate treatment options. In the peripheral nervous system the chemotherapeutic agent paclitaxel impairs mitochondrial function and induces vast chan...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-03-24 | PXD028356 | Pride
Rat Dia-ms Drg-proteome Cipn Hf-x 
ProteomicsDIA LC-MS analysis of post-incisional human and mouse skin biopsies
Acute postsurgerical pain and it's management represent a major clinical challenge. In particular, severe and prolonged pain impairs immediate recovery and might lead to long-term consequences like chronic pain, opioid abuse, and reduced quality of life. Rodent incision models greatly contributed ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-03-07 | PXD030828 | Pride
Pain Bi-translational Lc-ms Incision Human Cutaneous protein signatures Mouse Hf-x 
ProteomicsXpo7 is a broad-spectrum exportin and a nuclear import receptor
Cargo molecules which exceed the passive diffusion limit of ~5nm require active translocation to cross the nuclear pore complex (NPC). Such a facilitated transport is achieved by specialized nuclear transport receptors (NTRs), which are classified according to their shuttling direction. Exportins bi...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-07 | PXD008746 | Pride
Lc-msms Importin Exportin Nanobodies Npcs Erythropoiesis Rangtpase Mouse 
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