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ProteomicsChemerin effect on the endometrial proteome of the domestic pig during implantation obtained by LC-MS/MS analysis
Chemerin (CHEM) is a hormone mainly expressed in adipocytes involved in the regulation of energy homeostasis and inflammatory response. CHEM expression has been demonstrated in the structures of the porcine hypothalamic-pituitary-gonadal axis, as well as in the uterus, trophoblasts and conceptuses o...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-04-26 | PXD031795 | Pride
Endometrium Tmt Lc-ms Chemerin Pig 
ProteomicsLC-MS/MS analysis of Aedes aegypti
TMT10plex-based shotgun quantitative proteomics of three species of Aedes aegypti.
ORGANISM(S): Aedes aegypti 
2021-10-08 | PXD025994 | Pride
Tmt10plex Aedes aegypti Proteomics 
ProteomicsHiRIEF-LC-MS based proteomics on Small Intestinal Neuroendocrine Tumors (SI-NET) and SI-NET cell lines
Part I - SI-NET tumors High Resolution Isoelectric Focusing (HiRIEF) LC-MS and relative quantification by iTRAQ 8-plex was used to analyze 14 small intestinal neuroendocrine tumors (SI-NETs). The data was obtained from two separate TMT10plex sets and linked by a single internal pooled standard. The ...
ORGANISM(S): Homo sapiens (Human) 
2020-12-09 | PXD009877 | Pride
Human Cancer Si-net Clinical Pevonedistat Mln4924 Timecourse 
ProteomicsQuantitative mass spectrometric analysis of UBE2S auto-ubiquitination throughout the cell cycle.
Immunoprecipitated UBE2S from HeLa K cells synchronized in pro metaphase, anaphase and G1-phase, were analyzed by tryptic digest and LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2022-03-23 | PXD012643 | Pride
Hela Ubiquitination Ube2s Lc-ms/ms 
ProteomicsMouse HiRIEF LCMS Proteomics of liver tissue - WT VS PolgA KO mutant
Mitochondrial dysfunction is implicated in aging and aging-related disorders, such as neurodegenerative diseases and stroke. To study the effects of progressive mitochondrial dysfunction, a homozygous knock-in mouse expressing a proof-reading deficient version of the nucleus-encoded catalytic subuni...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-05 | PXD047574 | Pride
Mouse Tmt10plex Liver Wild type Hirief Lcms Murine Polga knockout Wt Qexactive 
ProteomicsHiRIEF-LC-MS based proteomics on Small Intestinal Neuroendocrine Tumors (SI-NET) and SI-NET cell lines
Associated to PXD009877 which contains Part I and Part II. Part III – Pevonedistat/MLN4924 and Bortezomib treatment of the SI-NET (small intestinal – neuroendocrine tumor) cell line CNDT2. High Resolution Isoelectric Focusing (HiRIEF) LC-MS and relative quantification by TMT 10-plex was used to an...
ORGANISM(S): Homo sapiens (Human) 
2021-06-10 | PXD013024 | Pride
Human Pevonedistat Neuro endocrine tumor Bortezomib Cell line 
ProteomicsLC-MS/MS - NS-NE - Zika Virus Impairs Neurogenesis and Synaptogenesis Pathways in Human Neural Stem Cells and Neurons
Growing evidences have associated Zika virus infection with congenital malformations, including microcephaly. Nonetheless, signaling mechanisms that promote the disease outcome are far from being understood, affecting the development of suitable therapeutics. In this study, we applied shotgun mass s...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD009293 | Pride
Lc-ms/ms 
Proteomicsproteome analysis using mass spectrometry (MS) in acute shYthdf2-mediated knockdown of cultured RGCs
To identify mouse retinal proteomics changes after Ythdf2 knockdown, we extracted the proteomics of E15.5 retina neurons which were cultured and infected with lentiviral shYthdf2 or shCtrl by urea. After using 100 mM TEAB (Sigma) to dilute the urea concentration to less than 2 M in each sample, tryp...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD017775 | Pride
Mouse  retina  ythdf2  knockdown 
ProteomicsProteomics on post-mortem human brain tissue of patients with Alzheimer`s, Parkinson`s and Lewy body dementias.
We have used HiRIEF (High Resolution Isoelectric Focusing) LC-MS proteomics with isobaric tags (TMT10plex) to compare 32 post-mortem human brains in the prefrontal cortex (Brodmann area 9) of prospectively followed patients with Alzheimer`s disease (AD), Parkinson`s disease with dementia (PDD), deme...
ORGANISM(S): Homo sapiens (Human) 
2017-12-08 | PXD006122 | Pride
Synaptic Lewy body Proteomics Brain Prefrontal cortex Alzheimer Brodmann area 9 Parkinson Hirief Lcms Human 
ProteomicsMytilus galloprovincialis cryopreserved oocytes LC-MS/MS data
Cryopreservation of gametes offers significant potential for genetic diversity conservation and selective breeding in aquaculture. The blue mussel, Mytilus galloprovincialis, is valuable in the aquaculture industry, but declining seed availability and the need for efficient hatchery production, espe...
ORGANISM(S): Mytilus galloprovincialis (Mediterranean mussel) 
2025-08-29 | PXD053176 | Pride
Cryoprotectant agent In vitro fertilisation Oxidative stress Mytilus galloprovincialis Cytotoxicity 
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