Sort   by:  
 Page size 
ProteomicsRawBeans: a simple, vendor independent, raw-data quality control tool
Every laboratory performing mass spectrometry based proteomics strives to generate high quality data. Among the many factors that influence the outcome of any experiment in proteomics is performance of the LC-MS system, which should be monitored continuously. This process is termed quality control (...
ORGANISM(S): Homo sapiens (Human) 
2021-03-11 | PXD022816 | Pride
Qc Quality control 
ProteomicsIntensity-based label-free proteomics using a quadrupole orbitrap mass spectrometer
We present a unique data set for benchmarking label free quantitative proteomics using a quadrupole orbitrap mass spectrometer. Soluble Escherichia coli digest was spiked into a HeLa digest in four different concentrations, simulating protein expression differences. The data set, which is available ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2015-03-25 | PXD001385 | Pride
Q exactive Quadrupole orbitrap Proteomics Label-free 
ProteomicsSuspension trapping (S-trap) is compatible with typical protein extraction buffers and detergents for bottom up proteomics
Analysis of cells and tissue by bottom up proteomics starts with lysis, followed by in-solution digestion. Lysis buffers commonly used include detergents and other reagents for efficient solubility of the proteins. However these reagents are, for the most part, incompatible with downstream analytica...
ORGANISM(S): Homo sapiens (Human) 
2019-02-28 | PXD011665 | Pride
Q eaxctive hf Lysis Proteomics Hela S-trap 
ProteomicsIdentification of a biomarker in cerebrospinal fluid for neuronopathic forms of Gaucher disease
Gaucher disease, a recessive inherited metabolic disorder caused by defects in the gene encoding glucosylceramidase (GlcCerase), can be divided into three subtypes according to the appearance of symptoms associated with central nervous system involvement. We now identify a protein, glycoprotein non-...
ORGANISM(S): Homo sapiens (Human) 
2016-06-24 | PXD001654 | Pride
Csf Gaucher Proteomics 
ProteomicsGlycoproteome-Wide Discovery of Cortical Glycoproteins That May Provide Cognitive Resilience in Older Adults
Background and Objectives Molecular omics studies have identified proteins related to cognitive resilience but unrelated to Alzheimer disease and Alzheimer disease–related dementia (AD/ADRD) pathologies. Posttranslational modifications of proteins with glycans can modify protein function. In this s...
ORGANISM(S): Homo sapiens (Human) 
2025-12-24 | PXD072371 | Pride
Brain Ad Glycoproteomics Human Cognition 
ProteomicsPhaeodactylum tricornutum oxidative stress
A study to investigate redox reactions in Phaeodactylum tricornutum diatom using OxiCAT method.Diatoms are ubiquitous marine photosynthetic eukaryotes that are responsible for about 20% of photosynthesis on Earth and therefore are an important component of the large biogeochemical cycles in the ocea...
ORGANISM(S): Phaeodactylum tricornutum 
2014-01-23 | PXD000191 | Pride
Phaeodactylum tricornutum  lc-ms/ms  redox Oxicat 
ProteomicsIdentification of a biomarker in cerebrospinal fluid for neuronopathic forms of Gaucher disease
Gaucher disease, a recessive inherited metabolic disorder caused by defects in the gene encoding glucosylceramidase (GlcCerase), can be divided into three subtypes according to the appearance of symptoms associated with central nervous system involvement. We now identify a protein, glycoprotein non-...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080786 | MassIVE
ProteomicsChronic iron limitation induces resistance to ROS
Diatoms are single celled photosynthetic bloom-forming algae that are responsible for at least 20% of global primary production. Nevertheless, more than 30% of the oceans are considered “ocean deserts” due to iron limitation. We used the diatom Phaeodactylum tricornutum as a model system to explore ...
ORGANISM(S): Phaeodactylum tricornutum (strain CCAP 1055/1) 
2017-01-16 | PXD004694 | Pride
Proteomics Diatom 
ProteomicsNext Generation Protein Sequencing
NGPS is a method for de-novo, full-length protein sequencing in high throughput. The method is based on cleavage of the protein at semi-random sites by microwave-assisted acid hydrolysis (MAAH), enrichment of LC-MS/MS amenable peptides from the hydrolysate by solid-phase-extraction, LC-MS/MS analysi...
ORGANISM(S): Bos taurus (Bovine) Equus caballus (Horse) 
2017-04-03 | PXD003804 | Pride
Full length Maah De-novo Ngps Microwave 
ProteomicsAn optimized glycopeptide enrichment method – it’s all about the sauce
Protein glycosylation is a family of post translational modifications (PTMs) that play a crucial role in cellular and tissue biology, and whose role in disease is unraveled with every new finding. Enrichment and analysis of such a diverse family of modification is very challenging, due to the number...
ORGANISM(S): Homo sapiens (Human) 
2022-06-29 | PXD031177 | Pride
Glycation Brain Glycopeptide Ptm Boronic acid Plasma 
Sort   by:  
 Page size