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ProteomicsStructural Polymorphism of ALECT2 Amyloid Fibrils Revealed by Cryo-EM: Implications for Disease Pathogenesis
1. Identification of tryptic and chymotryptic fragments in ALECT2 fibrils (Figure 1, Q Exactive HF) For tryptic: Sample ID 1176342 For Chymotryptic: Sample ID 1176352 2. Intact mass analysis of ALECT2 fibrils from the kidney (Supplementary figure 1 and supplementary table 1, X500B QTOF) Sample ID:...
ORGANISM(S): Homo Sapiens 
2025-06-16 | MSV000098220 | MassIVE
ProteomicsAssessing the relationship between mass window width and retention time scheduling on protein coverage for data-independent acquisition
Due to the technical advances of mass spectrometers especially the high scanning speed and high MS/MS resolution, the data independent acquisition mass spectrometry (DIA-MS) began to be widely used, which enables high reproducibility in both proteomic identification and quantification. The current D...
ORGANISM(S): Homo sapiens (Human) 
2019-07-01 | PXD013477 | Pride
Scheduling Rtwindia Window size Oribtrap fusion lumos Dia-ms 
ProteomicsUD1long pulldown from HeLa Cell Extract
Here we used a his-tagged version of the UD1long UBE2D inhibitor to pulldown protein from HeLa cell extract
ORGANISM(S): Homo sapiens (Human) 
2025-12-11 | PXD065412 | Pride
Ube2d Ubiquitin Linked-domain inhibitors 
ProteomicsPeptide Ancestry Informative Markers in Uterine Neoplasms from Women of European, African and Asian Ancestry
Characterization of ancestry-linked peptide variants in disease-relevant patient tissues represents a foundational step to connect patient ancestry with molecular disease pathogenesis. Nonsynonymous single nucleotide polymorphisms (SNPs) encoding missense substitutions within tryptic peptides exhibi...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD029323 | Pride
Tmt-11 Tmt-10 Fibroid Endometrial cancer cell line Uterine leiomyoma Quantitative proteomics 
ProteomicsLCMS Analysis of V5-KEAP1 +/- Drug, Wood Lab
Coomassie stained SDS-PAGE bands were subjected to standardized in-gel trypsin digestion in which gel bands were subjected to reduction with 10 mM dithiolthreitol, alkylated with 20 mM iodoacetamide, and digested with 100ng of sequencing grade modified trypsin (Promega). Extracted peptides were lyop...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-12-01 | MSV000100060 | MassIVE
ProteomicsProteomic analysis of Neoporphyra haitanensis under desiccation stress
Colonization of land from marine environments was a major transition for biological life on Earth, and intertidal adaptation was a key evolutionary event in the transition from marine- to land-based lifestyles. Multicellular intertidal red algae exhibit the earliest, systematic, and successful adapt...
ORGANISM(S): Pyropia haitanensis 
2022-02-16 | PXD028649 | Pride
Lc-msms Thalli Desiccation Neoporphyra haitanensis 
ProteomicsIdentification of Sulphostin targets unsig competitive ABPP
Covalent chemical probes and drugs combine unique pharmacologic properties with the availability of straightforward compound profiling technologies via chemoproteomic platforms. These advantages have fostered the development of suitable electrophilic ‘warheads’ for systematic covalent chemical probe...
ORGANISM(S): Homo sapiens (Human) 
2025-02-25 | PXD058896 | Pride
Inhibitor development Natural product Dipeptidyl peptidase Activity-based protein profiling Target identification 
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